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aar2 AAR2 splicing factor [ Danio rerio (zebrafish) ]

Gene ID: 431768, updated on 8-Mar-2025

Summary

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Official Symbol
aar2provided by ZNC
Official Full Name
AAR2 splicing factorprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040704-68
See related
Ensembl:ENSDARG00000018658 AllianceGenome:ZFIN:ZDB-GENE-040704-68
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:92018; im:7153138
Summary
Predicted to be involved in spliceosomal tri-snRNP complex assembly. Orthologous to human AAR2 (AAR2 splicing factor). [provided by Alliance of Genome Resources, Mar 2025]
Orthologs
human mouse all
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Genomic context

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See aar2 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (4216196..4225571, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (4276949..4286705, complement)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108181461 Neighboring gene uncharacterized LOC137489081 Neighboring gene zgc:113278 Neighboring gene ADP-ribosylation factor-like 6 interacting protein 5b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in spliceosomal tri-snRNP complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
protein AAR2 homolog
Names
AAR2 splicing factor homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002221.1 → NP_001002221.1  protein AAR2 homolog

    See identical proteins and their annotated locations for NP_001002221.1

    Status: PROVISIONAL

    Source sequence(s)
    BC072724
    UniProtKB/TrEMBL
    Q6GQL8
    Related
    ENSDARP00000013455.5, ENSDART00000014152.7
    Conserved Domains (3) summary
    cd13777
    Location:19 → 144
    Aar2_N; N-terminal domain of Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor
    cd13778
    Location:205 → 359
    Aar2_C; C-terminal domain of Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor
    pfam05282
    Location:17 → 364
    AAR2; AAR2 protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    4216196..4225571 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005161924.5 → XP_005161981.1  protein AAR2 homolog isoform X1

    UniProtKB/TrEMBL
    A0A8M2B915, F1R8D9
    Related
    ENSDARP00000132833.1, ENSDART00000170455.2
    Conserved Domains (3) summary
    cd13777
    Location:19 → 144
    Aar2_N; N-terminal domain of Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor
    cd13778
    Location:205 → 359
    Aar2_C; C-terminal domain of Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor
    pfam05282
    Location:17 → 364
    AAR2; AAR2 protein
Nucleotide Protein Strain
Heading Accession and Version

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