mapre3b microtubule-associated protein, RP/EB family, member 3b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mapre3bprovided by ZNC
Official Full Name: microtubule-associated protein, RP/EB family, member 3bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040704-6
See related: Ensembl:ENSDARG00000102878 AllianceGenome:ZFIN:ZDB-GENE-040704-6
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fj35g02; zgc:91952; wu:fj35g02
Summary: Predicted to enable microtubule plus-end binding activity. Predicted to be involved in protein localization to microtubule; regulation of microtubule polymerization or depolymerization; and spindle assembly. Predicted to act upstream of or within cell division. Predicted to be located in cytoplasm and microtubule. Predicted to be active in microtubule cytoskeleton. Orthologous to human MAPRE3 (microtubule associated protein RP/EB family member 3). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2025_04	current	GRCz12tu (GCF_049306965.1)	4	NC_133179.1 (1039169..1053289, complement)
RS_2024_08	previous assembly	GRCz11 (GCF_000002035.6)	4	NC_007115.7 (783643..797875, complement)

Chromosome 4 - NC_133179.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fj35g02.x1 (e-PCR)
- UniSTS:204628

fe05a06.x1 (e-PCR)
- UniSTS:195963

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables microtubule binding	IEA Inferred from Electronic Annotation more info
enables microtubule plus-end binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell division	IEA Inferred from Electronic Annotation more info
involved_in protein localization to microtubule	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of microtubule polymerization or depolymerization	IBA Inferred from Biological aspect of Ancestor more info
involved_in spindle assembly	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytoplasmic microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in microtubule	IEA Inferred from Electronic Annotation more info
located_in microtubule end	IEA Inferred from Electronic Annotation more info
is_active_in microtubule organizing center	IBA Inferred from Biological aspect of Ancestor more info
is_active_in microtubule plus-end	IBA Inferred from Biological aspect of Ancestor more info
is_active_in spindle midzone	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: microtubule-associated protein RP/EB family member 3b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002170.1 → NP_001002170.1 microtubule-associated protein RP/EB family member 3b

See identical proteins and their annotated locations for NP_001002170.1

Status: PROVISIONAL

Source sequence(s)

BC074053

UniProtKB/TrEMBL

A0A0R4IH21, A0A0R4IZD2, A0A8M9Q0D6, Q5RGY7, Q6GMJ3

Related

ENSDARP00000141399.1, ENSDART00000170012.2

Conserved Domains (1) summary

cl26556
Location:16 → 253

EB1; EB1-like C-terminal motif

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

NC_133179.1 Reference GRCz12tu Primary Assembly

Range

1039169..1053289 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021474991.3 → XP_021330666.1 microtubule-associated protein RP/EB family member 3b isoform X2

UniProtKB/TrEMBL

A0A0R4IH21, A0A0R4IZD2, A0A8M9Q0D6, Q5RGY7, Q6GMJ3

Related

ENSDARP00000133923.1

Conserved Domains (1) summary

cl26556
Location:16 → 253

EB1; EB1-like C-terminal motif
XM_021474990.3 → XP_021330665.2 microtubule-associated protein RP/EB family member 3b isoform X1

UniProtKB/TrEMBL

A0A8M9Q0D6
XM_021474989.3 → XP_021330664.2 microtubule-associated protein RP/EB family member 3b isoform X1

UniProtKB/TrEMBL

A0A8M9Q0D6