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AFDN afadin, adherens junction formation factor [ Canis lupus familiaris (dog) ]

Gene ID: 431695, updated on 27-Jun-2026
Official Symbol
AFDNprovided by VGNC
Official Full Name
afadin, adherens junction formation factorprovided by VGNC
Primary source
VGNC:VGNC:37685
See related
Ensembl:ENSCAFG00845004971 RGD:12071677
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See AFDN in Genome Data Viewer
Location:
chromosome: 1
Exon count:
35
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (55579883..55717395)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (56188344..56325812)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (55950758..56088230)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (55476722..55614176)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (55323987..55461386)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119870668 Neighboring gene uncharacterized LOC111095989 Neighboring gene kinesin family member 25 Neighboring gene uncharacterized LOC119870772 Neighboring gene uncharacterized LOC119870159 Neighboring gene FERM domain containing 1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Involvement of the interaction of afadin with ZO-1 in the formation of tight junctions in Madin-Darby canine kidney cells. Ooshio T, et al. J Biol Chem, 2010 Feb 12. PMID 20008323, Free PMC Article
  2. Cooperative roles of Par-3 and afadin in the formation of adherens and tight junctions. Ooshio T, et al. J Cell Sci, 2007 Jul 15. PMID 17606991
  3. Regulation of the assembly and adhesion activity of E-cadherin by nectin and afadin for the formation of adherens junctions in Madin-Darby canine kidney cells. Sato T, et al. J Biol Chem, 2006 Feb 24. PMID 16361708
  4. Afadin orients cell division to position the tubule lumen in developing renal tubules. Gao L, et al. Development, 2017 Oct 1. PMID 28860115, Free PMC Article
  5. Light-activated BioID - an optically activated proximity labeling system to study protein-protein interactions. Shafraz O, et al. J Cell Sci, 2023 Oct 1. PMID 37756605, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. afadin determines lumen placement by directing apical-basal spindle orientation, resulting in a continuous lumen and normal tubule morphogenesis.
    Title: Afadin orients cell division to position the tubule lumen in developing renal tubules.
  2. The results indicate that the transient interaction of afadin with ZO-1 is necessary for the formation of Tight junctions in MDCK cells.
    Title: Involvement of the interaction of afadin with ZO-1 in the formation of tight junctions in Madin-Darby canine kidney cells.
  3. findings show that Par-3 and afadin cooperatively regulate the formation of tight junctions, similarly to their roles in the formation of adherens junctions
    Title: Cooperative roles of Par-3 and afadin in the formation of adherens and tight junctions.
  4. nectin regulates the assembly and cell-cell adhesion activity of E-cadherin through afadin, nectin signaling, and p120(ctn) for the formation of adherens junctions
    Title: Regulation of the assembly and adhesion activity of E-cadherin by nectin and afadin for the formation of adherens junctions in Madin-Darby canine kidney cells.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of protein localization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
afadin
Names
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
myeloid/lymphoid or mixed-lineage leukemia 4

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    55579883..55717395
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038654641.1 → XP_038510569.1  afadin isoform X1

    UniProtKB/TrEMBL
    A0A8I3MS32, A0A8I3MW05
    Related
    ENSCAFP00845007058.1, ENSCAFT00845008952.1
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1526 → 1699
    DUF5401; Family of unknown function (DUF5401)
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)

  2. XM_038654645.1 → XP_038510573.1  afadin isoform X5

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1524 → 1697
    DUF4670; Domain of unknown function (DUF4670)

  3. XM_038654642.1 → XP_038510570.1  afadin isoform X2

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1524 → 1698
    DUF4670; Domain of unknown function (DUF4670)

  4. XM_038654647.1 → XP_038510575.1  afadin isoform X7

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1478 → 1696
    DUF5401; Family of unknown function (DUF5401)
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)

  5. XM_038654649.1 → XP_038510577.1  afadin isoform X9

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1524 → 1687
    DUF4670; Domain of unknown function (DUF4670)

  6. XM_038654651.1 → XP_038510579.1  afadin isoform X11

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    COG3064
    Location:1524 → 1684
    TolA; Membrane protein involved in colicin uptake [Cell wall/membrane/envelope biogenesis]
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)

  7. XM_038654659.1 → XP_038510587.1  afadin isoform X18

    UniProtKB/TrEMBL
    A0A8I3MS32
    Related
    ENSCAFP00845007078.1, ENSCAFT00845008977.1
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1461 → 1634
    DUF5401; Family of unknown function (DUF5401)
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)

  8. XM_038654648.1 → XP_038510576.1  afadin isoform X8

    UniProtKB/TrEMBL
    A0A8I3MS32
    Related
    ENSCAFP00845007169.1, ENSCAFT00845009095.1
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 933
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1519 → 1692
    DUF5401; Family of unknown function (DUF5401)
    pfam00595
    Location:1009 → 1091
    PDZ; PDZ domain (Also known as DHR or GLGF)

  9. XM_038654654.1 → XP_038510582.1  afadin isoform X14

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    COG3064
    Location:1517 → 1677
    TolA; Membrane protein involved in colicin uptake [Cell wall/membrane/envelope biogenesis]
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 933
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:1009 → 1091
    PDZ; PDZ domain (Also known as DHR or GLGF)

  10. XM_038654652.1 → XP_038510580.1  afadin isoform X12

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:385 → 485
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:597 → 925
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1511 → 1684
    DUF5401; Family of unknown function (DUF5401)
    pfam00595
    Location:1001 → 1083
    PDZ; PDZ domain (Also known as DHR or GLGF)

  11. XM_038654658.1 → XP_038510586.1  afadin isoform X17

    UniProtKB/TrEMBL
    A0A8I3MS32
    Related
    ENSCAFP00845007127.1, ENSCAFT00845009041.1
    Conserved Domains (6) summary
    cd00060
    Location:385 → 485
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:597 → 925
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:1001 → 1083
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1509 → 1672
    DUF4670; Domain of unknown function (DUF4670)

  12. XM_038654644.1 → XP_038510572.1  afadin isoform X4

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:417 → 499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:611 → 939
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:247 → 347
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1525 → 1698
    DUF5401; Family of unknown function (DUF5401)
    pfam00595
    Location:1015 → 1097
    PDZ; PDZ domain (Also known as DHR or GLGF)

  13. XM_038654643.1 → XP_038510571.1  afadin isoform X3

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:417 → 499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:611 → 939
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:247 → 347
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1525 → 1698
    DUF5401; Family of unknown function (DUF5401)
    pfam00595
    Location:1015 → 1097
    PDZ; PDZ domain (Also known as DHR or GLGF)

  14. XM_038654650.1 → XP_038510578.1  afadin isoform X10

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:417 → 499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:611 → 939
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:247 → 347
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:1015 → 1097
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1523 → 1686
    DUF4670; Domain of unknown function (DUF4670)

  15. XM_038654653.1 → XP_038510581.1  afadin isoform X13

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:417 → 499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:611 → 932
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:247 → 347
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:1008 → 1090
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1516 → 1679
    DUF4670; Domain of unknown function (DUF4670)

  16. XM_038654655.1 → XP_038510583.1  afadin isoform X15

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    COG3064
    Location:1516 → 1676
    TolA; Membrane protein involved in colicin uptake [Cell wall/membrane/envelope biogenesis]
    cd00060
    Location:417 → 499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:611 → 932
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:247 → 347
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:1008 → 1090
    PDZ; PDZ domain (Also known as DHR or GLGF)

  17. XM_038654646.1 → XP_038510574.1  afadin isoform X6

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:416 → 498
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:610 → 938
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:246 → 346
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1524 → 1697
    DUF5401; Family of unknown function (DUF5401)
    pfam00595
    Location:1014 → 1096
    PDZ; PDZ domain (Also known as DHR or GLGF)

  18. XM_038654657.1 → XP_038510585.1  afadin isoform X16

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:383 → 483
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:595 → 916
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:246 → 346
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1502 → 1675
    DUF5401; Family of unknown function (DUF5401)
    pfam00595
    Location:992 → 1074
    PDZ; PDZ domain (Also known as DHR or GLGF)

  19. XM_038654660.1 → XP_038510588.1  afadin isoform X19

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:383 → 483
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:595 → 916
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:246 → 346
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:992 → 1074
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1500 → 1663
    DUF4670; Domain of unknown function (DUF4670)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    55476722..55614176
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038465873.1 → XP_038321801.1  

  2. XM_038465877.1 → XP_038321805.1  

  3. XM_038465874.1 → XP_038321802.1  

  4. XM_038465879.1 → XP_038321807.1  

  5. XM_038465881.1 → XP_038321809.1  

  6. XM_038465883.1 → XP_038321811.1  

  7. XM_038465890.1 → XP_038321818.1  

  8. XM_038465880.1 → XP_038321808.1  

  9. XM_038465886.1 → XP_038321814.1  

  10. XM_038465884.1 → XP_038321812.1  

  11. XM_038465889.1 → XP_038321817.1  

  12. XM_038465876.1 → XP_038321804.1  

  13. XM_038465875.1 → XP_038321803.1  

  14. XM_038465882.1 → XP_038321810.1  

  15. XM_038465885.1 → XP_038321813.1  

  16. XM_038465887.1 → XP_038321815.1  

  17. XM_038465878.1 → XP_038321806.1  

  18. XM_038465888.1 → XP_038321816.1  

  19. XM_038465891.1 → XP_038321819.1  

    Conserved Domains (6) summary
    cd00060
    Location:383 → 483
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:595 → 916
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:246 → 346
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:992 → 1074
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1500 → 1663
    DUF4670; Domain of unknown function (DUF4670)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    55323987..55461386
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038590845.1 → XP_038446773.1  

  2. XM_038590849.1 → XP_038446777.1  

  3. XM_038590846.1 → XP_038446774.1  

  4. XM_038590851.1 → XP_038446779.1  

  5. XM_038590853.1 → XP_038446781.1  

  6. XM_038590855.1 → XP_038446783.1  

  7. XM_038590862.1 → XP_038446790.1  

  8. XM_038590852.1 → XP_038446780.1  

  9. XM_038590858.1 → XP_038446786.1  

  10. XM_038590856.1 → XP_038446784.1  

  11. XM_038590861.1 → XP_038446789.1  

  12. XM_038590848.1 → XP_038446776.1  

  13. XM_038590847.1 → XP_038446775.1  

  14. XM_038590854.1 → XP_038446782.1  

  15. XM_038590857.1 → XP_038446785.1  

  16. XM_038590859.1 → XP_038446787.1  

  17. XM_038590850.1 → XP_038446778.1  

  18. XM_038590860.1 → XP_038446788.1  

  19. XM_038590863.1 → XP_038446791.1  

    Conserved Domains (6) summary
    cd00060
    Location:383 → 483
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:595 → 916
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:246 → 346
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:992 → 1074
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1500 → 1663
    DUF4670; Domain of unknown function (DUF4670)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    55950758..56088230
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038526552.1 → XP_038382480.1  afadin isoform X1

    UniProtKB/TrEMBL
    A0A8I3MS32

  2. XM_038526556.1 → XP_038382484.1  afadin isoform X5

    UniProtKB/TrEMBL
    A0A8I3MS32

  3. XM_038526553.1 → XP_038382481.1  afadin isoform X2

    UniProtKB/TrEMBL
    A0A8I3MS32

  4. XM_038526558.1 → XP_038382486.1  afadin isoform X7

    UniProtKB/TrEMBL
    A0A8I3MS32

  5. XM_038526560.1 → XP_038382488.1  afadin isoform X9

    UniProtKB/TrEMBL
    A0A8I3MS32

  6. XM_038526562.1 → XP_038382490.1  afadin isoform X11

    UniProtKB/TrEMBL
    A0A8I3MS32

  7. XM_038526569.1 → XP_038382497.1  afadin isoform X18

    UniProtKB/TrEMBL
    A0A8I3MS32

  8. XM_038526559.1 → XP_038382487.1  afadin isoform X8

    UniProtKB/TrEMBL
    A0A8I3MS32

  9. XM_038526565.1 → XP_038382493.1  afadin isoform X14

    UniProtKB/TrEMBL
    A0A8I3MS32

  10. XM_038526563.1 → XP_038382491.1  afadin isoform X12

    UniProtKB/TrEMBL
    A0A8I3MS32

  11. XM_038526568.1 → XP_038382496.1  afadin isoform X17

    UniProtKB/TrEMBL
    A0A8I3MS32

  12. XM_038526555.1 → XP_038382483.1  afadin isoform X4

    UniProtKB/TrEMBL
    A0A8I3MS32

  13. XM_038526554.1 → XP_038382482.1  afadin isoform X3

    UniProtKB/TrEMBL
    A0A8I3MS32

  14. XM_038526561.1 → XP_038382489.1  afadin isoform X10

    UniProtKB/TrEMBL
    A0A8C0L9V9, A0A8I3MS32

  15. XM_038526564.1 → XP_038382492.1  afadin isoform X13

    UniProtKB/TrEMBL
    A0A8I3MS32

  16. XM_038526566.1 → XP_038382494.1  afadin isoform X15

    UniProtKB/TrEMBL
    A0A8I3MS32

  17. XM_038526557.1 → XP_038382485.1  afadin isoform X6

    UniProtKB/TrEMBL
    A0A8I3MS32

  18. XM_038526567.1 → XP_038382495.1  afadin isoform X16

    UniProtKB/TrEMBL
    A0A8I3MS32

  19. XM_038526570.1 → XP_038382498.1  afadin isoform X19

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:383 → 483
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:595 → 916
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:246 → 346
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:992 → 1074
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1500 → 1663
    DUF4670; Domain of unknown function (DUF4670)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    56188344..56325812
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038534179.1 → XP_038390107.1  afadin isoform X1

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1526 → 1699
    DUF5401; Family of unknown function (DUF5401)
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)

  2. XM_038534468.1 → XP_038390396.1  afadin isoform X5

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1524 → 1697
    DUF4670; Domain of unknown function (DUF4670)

  3. XM_038534265.1 → XP_038390193.1  afadin isoform X2

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1524 → 1698
    DUF4670; Domain of unknown function (DUF4670)

  4. XM_038534603.1 → XP_038390531.1  afadin isoform X7

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1478 → 1696
    DUF5401; Family of unknown function (DUF5401)
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)

  5. XM_038534732.1 → XP_038390660.1  afadin isoform X9

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1524 → 1687
    DUF4670; Domain of unknown function (DUF4670)

  6. XM_038534822.1 → XP_038390750.1  afadin isoform X11

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    COG3064
    Location:1524 → 1684
    TolA; Membrane protein involved in colicin uptake [Cell wall/membrane/envelope biogenesis]
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)

  7. XM_038535272.1 → XP_038391200.1  afadin isoform X18

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 940
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1461 → 1634
    DUF5401; Family of unknown function (DUF5401)
    pfam00595
    Location:1016 → 1098
    PDZ; PDZ domain (Also known as DHR or GLGF)

  8. XM_038534678.1 → XP_038390606.1  afadin isoform X8

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 933
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1519 → 1692
    DUF5401; Family of unknown function (DUF5401)
    pfam00595
    Location:1009 → 1091
    PDZ; PDZ domain (Also known as DHR or GLGF)

  9. XM_038535010.1 → XP_038390938.1  afadin isoform X14

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    COG3064
    Location:1517 → 1677
    TolA; Membrane protein involved in colicin uptake [Cell wall/membrane/envelope biogenesis]
    cd00060
    Location:418 → 500
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:612 → 933
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:1009 → 1091
    PDZ; PDZ domain (Also known as DHR or GLGF)

  10. XM_038534877.1 → XP_038390805.1  afadin isoform X12

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:385 → 485
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:597 → 925
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1511 → 1684
    DUF5401; Family of unknown function (DUF5401)
    pfam00595
    Location:1001 → 1083
    PDZ; PDZ domain (Also known as DHR or GLGF)

  11. XM_038535205.1 → XP_038391133.1  afadin isoform X17

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:385 → 485
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:597 → 925
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:248 → 348
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:1001 → 1083
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1509 → 1672
    DUF4670; Domain of unknown function (DUF4670)

  12. XM_038534423.1 → XP_038390351.1  afadin isoform X4

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:417 → 499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:611 → 939
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:247 → 347
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 132
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1525 → 1698
    DUF5401; Family of unknown function (DUF5401)
    pfam00595
    Location:1015 → 1097
    PDZ; PDZ domain (Also known as DHR or GLGF)

  13. XM_038534338.1 → XP_038390266.1  afadin isoform X3

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:417 → 499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:611 → 939
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:247 → 347
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1525 → 1698
    DUF5401; Family of unknown function (DUF5401)
    pfam00595
    Location:1015 → 1097
    PDZ; PDZ domain (Also known as DHR or GLGF)

  14. XM_038534786.1 → XP_038390714.1  afadin isoform X10

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:417 → 499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:611 → 939
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:247 → 347
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:1015 → 1097
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1523 → 1686
    DUF4670; Domain of unknown function (DUF4670)

  15. XM_038534951.1 → XP_038390879.1  afadin isoform X13

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:417 → 499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:611 → 932
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:247 → 347
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:1008 → 1090
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1516 → 1679
    DUF4670; Domain of unknown function (DUF4670)

  16. XM_038535074.1 → XP_038391002.1  afadin isoform X15

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    COG3064
    Location:1516 → 1676
    TolA; Membrane protein involved in colicin uptake [Cell wall/membrane/envelope biogenesis]
    cd00060
    Location:417 → 499
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:611 → 932
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:247 → 347
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:1008 → 1090
    PDZ; PDZ domain (Also known as DHR or GLGF)

  17. XM_038534524.1 → XP_038390452.1  afadin isoform X6

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:416 → 498
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:610 → 938
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:246 → 346
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1524 → 1697
    DUF5401; Family of unknown function (DUF5401)
    pfam00595
    Location:1014 → 1096
    PDZ; PDZ domain (Also known as DHR or GLGF)

  18. XM_038535140.1 → XP_038391068.1  afadin isoform X16

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:383 → 483
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:595 → 916
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:246 → 346
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam17380
    Location:1502 → 1675
    DUF5401; Family of unknown function (DUF5401)
    pfam00595
    Location:992 → 1074
    PDZ; PDZ domain (Also known as DHR or GLGF)

  19. XM_038535333.1 → XP_038391261.1  afadin isoform X19

    UniProtKB/TrEMBL
    A0A8I3MS32
    Conserved Domains (6) summary
    cd00060
    Location:383 → 483
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15471
    Location:595 → 916
    Myo5p-like_CBD_afadin; cargo binding domain of myosin 5-like of afadin
    cd01781
    Location:246 → 346
    RA2_Afadin; Ras-associating (RA) domain 2 found in Afadin
    cd01782
    Location:20 → 131
    RA1_Afadin; Ras-associating (RA) domain 1 found in Afadin
    pfam00595
    Location:992 → 1074
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam15709
    Location:1500 → 1663
    DUF4670; Domain of unknown function (DUF4670)
Nucleotide Protein
Heading Accession and Version

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