IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon [Gallus gallus (chicken)] - Gene

Summary

Symbol: IKBKEprovided by CGNC
Full Name: inhibitor of nuclear factor kappa B kinase subunit epsilonprovided by CGNC
Primary source: CGNC:10056
See related: Ensembl:ENSGALG00010027110
Gene type: protein coding
RefSeq status: MODEL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 26

Exon count:: 20

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	26	NC_052557.1 (2511609..2521868)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	26	NC_052598.1 (2481652..2491919)

Chromosome 26 - NC_052557.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

RNA sequencing results revealed that the chicken IKBKE was more upregulated in the intestinal mucosal layer of Necrotic enteritis induced chicken lines that are resistant and sensitive to avian leukosis and Marek's disease.
Title: Expression analysis of cytosolic DNA-sensing pathway genes in the intestinal mucosal layer of necrotic enteritis-induced chicken.

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in peptidyl-serine phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: inhibitor of nuclear factor kappa-B kinase subunit epsilon

Names: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon

XP_040508901.1

EC 2.7.11.10

XP_040547151.2

EC 2.7.11.10

XP_040547152.1

EC 2.7.11.10

XP_428036.6

EC 2.7.11.10

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052557.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

2511609..2521868

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040652967.2 → XP_040508901.1 inhibitor of nuclear factor kappa-B kinase subunit epsilon

UniProtKB/TrEMBL

A0A8V1A9R1

Conserved Domains (2) summary

cl21453
Location:15 → 330

PKc_like; Protein Kinases, catalytic domain

cl28922
Location:308 → 383

Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
XM_428036.8 → XP_428036.6 inhibitor of nuclear factor kappa-B kinase subunit epsilon

Related

ENSGALP00010039973.1, ENSGALT00010065707.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052598.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

2481652..2491919

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040691218.2 → XP_040547152.1 inhibitor of nuclear factor kappa-B kinase subunit epsilon

UniProtKB/TrEMBL

A0A8V1A9R1

Conserved Domains (2) summary

cl21453
Location:15 → 330

PKc_like; Protein Kinases, catalytic domain

cl28922
Location:308 → 383

Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
XM_040691217.2 → XP_040547151.2 inhibitor of nuclear factor kappa-B kinase subunit epsilon