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TYK2 tyrosine kinase 2 [ Gallus gallus (chicken) ]

Gene ID: 430113, updated on 13-Apr-2026
Official Symbol
TYK2provided by CGNC
Official Full Name
tyrosine kinase 2provided by CGNC
Primary source
CGNC:53861
See related
Ensembl:ENSGALG00010002443
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
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Try the new Transcripts and proteins table
See TYK2 in Genome Data Viewer
Location:
chromosome: 30
Exon count:
25
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 30 NC_052561.1 (21342..40704, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 30 Unlocalized Scaffold NW_024096182.1 (101685..122619, complement)

Chromosome 30 - NC_052561.1Genomic Context describing neighboring genes Neighboring gene adrenodoxin-like protein, mitochondrial Neighboring gene ribonucleoprotein, PTB binding 1 Neighboring gene cell division cycle 37 Neighboring gene uncharacterized LOC107057631 Neighboring gene trafficking protein particle complex 5

Go to nucleotide: Graphics FASTA GenBank

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
non-receptor tyrosine-protein kinase TYK2
Names
Tyk-2-like tyrosine kinase
protein kinase

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052561.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    21342..40704 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025145739.3 → XP_025001507.2  non-receptor tyrosine-protein kinase TYK2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0X5W9, A0A8V0X9Z3
    Related
    ENSGALP00010003466.1, ENSGALT00010005627.1
    Conserved Domains (4) summary
    cd10381
    Location:456 → 558
    SH2_Jak_Tyk2; Src homology 2 (SH2) domain in Tyrosine Kinase 2 (Tyk2), a member of the Janus kinases (JAK)
    smart00295
    Location:78 → 305
    B41; Band 4.1 homologues
    cl17171
    Location:300 → 456
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:917 → 1197
    PKc_like; Protein Kinases, catalytic domain

  2. XM_025145744.3 → XP_025001512.2  non-receptor tyrosine-protein kinase TYK2 isoform X2

    Conserved Domains (4) summary
    cd10381
    Location:456 → 558
    SH2_Jak_Tyk2; Src homology 2 (SH2) domain in Tyrosine Kinase 2 (Tyk2), a member of the Janus kinases (JAK)
    smart00295
    Location:78 → 305
    B41; Band 4.1 homologues
    cl17171
    Location:300 → 456
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:615 → 892
    PKc_like; Protein Kinases, catalytic domain

RNA

  1. XR_005842211.2 RNA Sequence

    Related
    ENSGALT00010005626.1

  2. XR_005842212.2 RNA Sequence

  3. XR_005842213.2 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NW_024096182.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    101685..122619 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040694461.2 → XP_040550395.1  non-receptor tyrosine-protein kinase TYK2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0X9Z3
    Conserved Domains (4) summary
    cd10381
    Location:456 → 558
    SH2_Jak_Tyk2; Src homology 2 (SH2) domain in Tyrosine Kinase 2 (Tyk2), a member of the Janus kinases (JAK)
    smart00295
    Location:78 → 305
    B41; Band 4.1 homologues
    cl17171
    Location:300 → 456
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:917 → 1197
    PKc_like; Protein Kinases, catalytic domain

  2. XM_040694460.2 → XP_040550394.1  non-receptor tyrosine-protein kinase TYK2 isoform X3

    UniProtKB/TrEMBL
    A0A8V0X9Z3
    Conserved Domains (3) summary
    cd10381
    Location:485 → 587
    SH2_Jak_Tyk2; Src homology 2 (SH2) domain in Tyrosine Kinase 2 (Tyk2), a member of the Janus kinases (JAK)
    cl17171
    Location:329 → 485
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:946 → 1226
    PKc_like; Protein Kinases, catalytic domain

  3. XM_040694462.2 → XP_040550396.1  non-receptor tyrosine-protein kinase TYK2 isoform X4

    Conserved Domains (4) summary
    cd10381
    Location:485 → 587
    SH2_Jak_Tyk2; Src homology 2 (SH2) domain in Tyrosine Kinase 2 (Tyk2), a member of the Janus kinases (JAK)
    smart00295
    Location:207 → 334
    B41; Band 4.1 homologues
    cl17171
    Location:329 → 485
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:644 → 921
    PKc_like; Protein Kinases, catalytic domain

RNA

  1. XR_005856819.2 RNA Sequence

  2. XR_005856820.2 RNA Sequence

  3. XR_005856821.2 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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