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Osbp Oxysterol binding protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42985, updated on 4-Nov-2018

Summary

Official Symbol
Osbpprovided by FlyBase
Official Full Name
Oxysterol binding proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0020626
Locus tag
Dmel_CG6708
Gene type
protein coding
RNA name
oxysterol binding protein
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG6708; Dmel\CG6708; osbp; OSBP; OSBP-Dm

Genomic context

See Osbp in Genome Data Viewer
Location:
96B10-96B10; 3-86 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24934869..24938222, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20760591..20763944, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Mitotic spindle and nuclear protein Neighboring gene ncRNA Neighboring gene Topoisomerase related function 4-2 Neighboring gene uncharacterized protein Neighboring gene slingshot Neighboring gene Nicotinamide mononucleotide adenylyltransferase

Genomic regions, transcripts, and products

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the Osbp gene: The Osbp gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, A.thaliana, and frog.

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
lipid binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
sterol binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
sterol transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
Golgi organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
intracellular protein transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
sperm individualization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
perinuclear endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
oxysterol binding protein
Names
CG6708-PA
Osbp-PA
oxysterol-binding protein

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    24934869..24938222 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_057923.4NP_477271.1  oxysterol binding protein [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_477271.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VC05
    Related
    FBpp0084176, FBtr0084801
    Conserved Domains (3) summary
    cd13284
    Location:17113
    PH_OSBP_ORP4; Human Oxysterol binding protein and OSBP-related protein 4 Pleckstrin homology (PH) domain
    pfam00169
    Location:15107
    PH; PH domain
    pfam01237
    Location:399764
    Oxysterol_BP; Oxysterol-binding protein
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