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asp abnormal spindle [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42946, updated on 8-Oct-2018

Summary

Official Symbol
aspprovided by FlyBase
Official Full Name
abnormal spindleprovided by FlyBase
Primary source
FLYBASE:FBgn0000140
Locus tag
Dmel_CG6875
Gene type
protein coding
RNA name
abnormal spindle
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-96Aa; anon-WO0118547.279; Asp; ASP; CG6875; Dm Asp; Dmel\CG6875

Genomic context

See asp in Genome Data Viewer
Location:
96A19-96A20; 3-85 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24753849..24760513)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20579571..20586235)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene tolkin Neighboring gene tolloid Neighboring gene Allatostatin A Neighboring gene ncRNA

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
calmodulin binding IDA
Inferred from Direct Assay
more info
PubMed 
microtubule binding IDA
Inferred from Direct Assay
more info
PubMed 
microtubule binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
myosin light chain binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
actin filament reorganization involved in cell cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
astral microtubule nucleation IMP
Inferred from Mutant Phenotype
more info
PubMed 
brain morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
centrosome localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
cystoblast division IMP
Inferred from Mutant Phenotype
more info
PubMed 
establishment of meiotic spindle localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
establishment of mitotic spindle orientation IMP
Inferred from Mutant Phenotype
more info
PubMed 
female germ-line stem cell asymmetric division IMP
Inferred from Mutant Phenotype
more info
PubMed 
germarium-derived oocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
kinetochore organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
microtubule cytoskeleton organization IDA
Inferred from Direct Assay
more info
PubMed 
microtubule-based process ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
mitotic spindle organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
nuclear migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
oogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
ovarian fusome organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
spindle organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
centrosome IDA
Inferred from Direct Assay
more info
PubMed 
microtubule associated complex IDA
Inferred from Direct Assay
more info
PubMed 
microtubule associated complex ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
microtubule organizing center IDA
Inferred from Direct Assay
more info
PubMed 
spindle pole IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
abnormal spindle
Names
CG6875-PA
abnormal spindle protein
abnormal spindles
asp-PA

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    24753849..24760513
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079764.3NP_524488.3  abnormal spindle [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524488.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VC45
    UniProtKB/TrEMBL
    H0RNM3
    Related
    FBpp0084071, FBtr0084692
    Conserved Domains (4) summary
    smart00015
    Location:16891711
    IQ; Calmodulin-binding motif
    cd00014
    Location:866968
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam13868
    Location:10661435
    TPH; Trichohyalin-plectin-homology domain
    pfam15780
    Location:26122
    ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
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