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tld tolloid [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42945, updated on 26-Aug-2021

Summary

Official Symbol
tldprovided by FlyBase
Official Full Name
tolloidprovided by FlyBase
Primary source
FLYBASE:FBgn0003719
Locus tag
Dmel_CG6868
Gene type
protein coding
RNA name
tolloid
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG6868; CT21278; Dmel\CG6868; dTld; Tld; TLD; Tolloid
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Genomic context

See tld in Genome Data Viewer
Location:
96A19-96A19; 3-85 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24749731..24753510)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20575453..20579232)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene Rpb10 Neighboring gene tolkin Neighboring gene abnormal spindle Neighboring gene Allatostatin A

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

General protein information

Preferred Names
tolloid
Names
CG6868-PA
tld-PA
NP_524487.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    24749731..24753510
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079763.4NP_524487.2  tolloid [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524487.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P25723
    Related
    FBpp0084070, FBtr0084691
    Conserved Domains (5) summary
    smart00042
    Location:388474
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    cd04281
    Location:137338
    ZnMc_BMP1_TLD; Zinc-dependent metalloprotease; BMP1/TLD-like subfamily. BMP1 (Bone morphogenetic protein 1) and TLD (tolloid)-like metalloproteases play vital roles in extracellular matrix formation, by cleaving precursor proteins such as enzymes, structural proteins, ...
    pfam00431
    Location:478586
    CUB; CUB domain
    pfam01400
    Location:144339
    Astacin; Astacin (Peptidase family M12A)
    pfam14670
    Location:757792
    FXa_inhibition; Coagulation Factor Xa inhibitory site
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