Format

Send to:

Choose Destination

Dis3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42900, updated on 8-Oct-2017
Official Symbol
Dis3provided by FlyBase
Primary source
FLYBASE:FBgn0039183
Locus tag
Dmel_CG6413
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG6413; dDis3; dis3; Dmel\CG6413; dRrp44; Rrp44; taz; Taz
Location:
95F13-95F14
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24333433..24337248)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20159155..20162970)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene CG31132 gene product from transcript CG31132-RA Neighboring gene CG5728 gene product from transcript CG5728-RA Neighboring gene CG6432 gene product from transcript CG6432-RB Neighboring gene mir-1015 stem loop Neighboring gene Myosuppressin

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
3'-5'-exoribonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
 
endoribonuclease activity IDA
Inferred from Direct Assay
more info
PubMed 
exoribonuclease activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
defense response to virus IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic cell cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
nuclear RNA surveillance IMP
Inferred from Mutant Phenotype
more info
PubMed 
rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
 
regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
exosome (RNase complex) IDA
Inferred from Direct Assay
more info
PubMed 
nuclear exosome (RNase complex) IDA
Inferred from Direct Assay
more info
PubMed 
nuclear exosome (RNase complex) ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
nuclear lamina IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
CG6413 gene product from transcript CG6413-RA
Names
CG6413-PA
CG6413-PB
Dis3
Dis3 ribonuclease
Dis3-PA
Dis3-PB
tazman

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    24333433..24337248
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142989.4NP_651246.2  Dis3, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651246.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VC93
    Related
    FBpp0083989.1, FBtr0084605
    Conserved Domains (3) summary
    cd09862
    Location:9203
    PIN_Rrp44; PIN domain of yeast exosome subunit Rrp44 endoribonuclease and other eukaryotic homologs
    COG0557
    Location:249945
    VacB; Exoribonuclease R [Transcription]
    pfam00773
    Location:474802
    RNB; RNB domain
  2. NM_001275981.1NP_001262910.1  Dis3, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262910.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VC93
    Related
    FBpp0306666.1, FBtr0334599
    Conserved Domains (3) summary
    cd09862
    Location:9203
    PIN_Rrp44; PIN domain of yeast exosome subunit Rrp44 endoribonuclease and other eukaryotic homologs
    COG0557
    Location:249945
    VacB; Exoribonuclease R [Transcription]
    pfam00773
    Location:474802
    RNB; RNB domain
Support Center