CCR7 C-C motif chemokine receptor 7 [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: CCR7provided by CGNC
Official Full Name: C-C motif chemokine receptor 7provided by CGNC
Primary source: CGNC:53333
See related: Ensembl:ENSGALG00010022529
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: chCCR7
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 27

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	27	NC_052558.1 (4466688..4475421, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	27	NC_052599.1 (5628852..5637581, complement)

Chromosome 27 - NC_052558.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

After dendritic cells(DC) maturation expression levels of chCCR6 mRNA were down-regulated, whereas those of chCCR7 were up-regulated, suggesting that these two chemokine receptors play a similar role in the trafficking of chicken DC as they do in mammals.
Title: Chicken CCR6 and CCR7 are markers for immature and mature dendritic cells respectively.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables C-C motif chemokine 19 receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables chemokine (C-C motif) ligand 19 binding	IEA Inferred from Electronic Annotation more info	PubMed
enables chemokine (C-C motif) ligand 21 binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: C-C chemokine receptor type 7

Names: chemokine (C-C motif) receptor 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001198752.2 → NP_001185681.1 C-C chemokine receptor type 7 precursor

See identical proteins and their annotated locations for NP_001185681.1

Status: VALIDATED

Source sequence(s)

JAENSK010000365

UniProtKB/TrEMBL

E3VW39

Related

ENSGALP00010033143.1, ENSGALT00010054832.1

Conserved Domains (2) summary

pfam00001
Location:73 → 322

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl22924
Location:63 → 247

7TM_GPCR_Srd; Serpentine type 7TM GPCR chemoreceptor Srd

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052558.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

4466688..4475421 complement

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GenBank, FASTA, Sequence Viewer (Graphics)