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GJB2 gap junction protein beta 2 [ Gallus gallus (chicken) ]

Gene ID: 428083, updated on 5-Mar-2024

Summary

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Symbol
GJB2provided by CGNC
Full Name
gap junction protein beta 2provided by CGNC
Primary source
CGNC:53259
See related
Ensembl:ENSGALG00010007181
Gene type
protein coding
RefSeq status
INFERRED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
2
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (178837883..178842766)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (178869063..178873944)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101747286 Neighboring gene gap junction protein beta 6 Neighboring gene gap junction protein alpha 3 Neighboring gene zinc finger MYM-type containing 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular and functional characterization of gap junctions in the avian inner ear. Nickel R, et al. J Neurosci, 2006 Jun 7. PMID 16763027, Free PMC Article
  2. Charged Residues at the First Transmembrane Region Contribute to the Voltage Dependence of the Slow Gate of Connexins. Pinto BI, et al. J Biol Chem, 2016 Jul 22. PMID 27143357, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. the role of the charged residues at the end of TM-1 in voltage sensing in Cx26, Cx46, and Cx50.
    Title: Charged Residues at the First Transmembrane Region Contribute to the Voltage Dependence of the Slow Gate of Connexins.
  2. Coexpression of Cx26/Cx30 is unique to gap junctions in the vertebrate inner ear.
    Title: Molecular and functional characterization of gap junctions in the avian inner ear.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in cell communication IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of connexin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
gap junction beta-2 protein
Names
gap junction protein, beta 2, 26kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001270816.3 → NP_001257745.1  gap junction beta-2 protein

    Status: INFERRED

    Source sequence(s)
    JAENSK010000027
    UniProtKB/TrEMBL
    E1C2J9
    Conserved Domains (1) summary
    pfam00029
    Location:2 → 211
    Connexin

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    178837883..178842766
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040701558.2 → XP_040557492.1  gap junction beta-2 protein isoform X1

    UniProtKB/TrEMBL
    E1C2J9
    Conserved Domains (1) summary
    pfam00029
    Location:2 → 211
    Connexin

  2. XM_040701556.2 → XP_040557490.1  gap junction beta-2 protein isoform X1

    UniProtKB/TrEMBL
    E1C2J9
    Conserved Domains (1) summary
    pfam00029
    Location:2 → 211
    Connexin

  3. XM_040701553.2 → XP_040557487.1  gap junction beta-2 protein isoform X1

    UniProtKB/TrEMBL
    E1C2J9
    Related
    ENSGALP00010009541.1, ENSGALT00010017128.1
    Conserved Domains (1) summary
    pfam00029
    Location:2 → 211
    Connexin

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    178869063..178873944
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046908591.1 → XP_046764547.1  gap junction beta-2 protein isoform X1

    UniProtKB/TrEMBL
    E1C2J9

  2. XM_046908590.1 → XP_046764546.1  gap junction beta-2 protein isoform X1

    UniProtKB/TrEMBL
    E1C2J9

  3. XM_046908589.1 → XP_046764545.1  gap junction beta-2 protein isoform X1

    UniProtKB/TrEMBL
    E1C2J9
Nucleotide Protein
Heading Accession and Version

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