H3-3A H3.3 variant histone A [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: H3-3Aprovided by CGNC
Official Full Name: H3.3 variant histone Aprovided by CGNC
Primary source: CGNC:53218
See related: Ensembl:ENSGALG00010017538
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: H3-I; H3-V; H3-II; H3-IV; H3-VI; H3.3A; H3F3A; H3F3C; H3-III; H3-VII; H3-VIII
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	3	NC_052534.1 (16831676..16837679, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	3	NC_052575.1 (16746202..16752205, complement)

Chromosome 3 - NC_052534.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data suggest that the A20/ZFAND6 (zinc finger protein A20) promoter can be regulated by dietary factors; here, maternal diet high in zinc up-regulates acetylation of histone 3 in the A20 promoter of offspring chicks.
Title: Maternal high-zinc diet attenuates intestinal inflammation by reducing DNA methylation and elevating H3K9 acetylation in the A20 promoter of offspring chicks.
This study highlight the potential role of H3K27 methylation status in early feed stress responses in chicks and may be indicative of an epigenetic mechanism for later adaptation to feed intake stress.
Title: Fasting of 3-day-old chicks leads to changes in histone H3 methylation status.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info	PubMed
enables structural constituent of chromatin	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of nucleosome	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: histone H3.2

Names: H3 histone, family 3A; H3 histone, family 3C; histone H3 class I; histone H3.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001031482.3 → NP_001026653.2 histone H3.2

See identical proteins and their annotated locations for NP_001026653.2

Status: VALIDATED

Source sequence(s)

JAENSK010000062

UniProtKB/Swiss-Prot

P84247

UniProtKB/TrEMBL

Q92068

Conserved Domains (1) summary

PTZ00018
Location:1 → 136

PTZ00018; histone H3; Provisional

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

16831676..16837679 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015283737.4 → XP_015139223.2 histone H3.2 isoform X1

Related

ENSGALP00010024885.1, ENSGALT00010042395.1

Conserved Domains (1) summary

PTZ00018
Location:1 → 136

PTZ00018; histone H3; Provisional

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

16746202..16752205 complement

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GenBank, FASTA, Sequence Viewer (Graphics)