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GRM8 glutamate metabotropic receptor 8 [ Gallus gallus (chicken) ]

Gene ID: 427853, updated on 13-Apr-2026
Symbol
GRM8provided by CGNC
Full Name
glutamate metabotropic receptor 8provided by CGNC
Primary source
CGNC:13848
See related
Ensembl:ENSGALG00010001223
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See GRM8 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
12
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (21099878..21424088)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (21332150..21677564)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene plexin B2 Neighboring gene uncharacterized LOC121110877 Neighboring gene uncharacterized LOC121109516 Neighboring gene translation initiation factor IF-2-like Neighboring gene zinc finger protein 800 Neighboring gene protection of telomeres 1 Neighboring gene G protein-coupled receptor 37

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables group III metabotropic glutamate receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled glutamate receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of synaptic transmission, glutamatergic IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
metabotropic glutamate receptor 8
Names
glutamate receptor, metabotropic 8

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    21099878..21424088
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_425426.8 → XP_425426.3  metabotropic glutamate receptor 8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XA35
    Related
    ENSGALP00010001379.1, ENSGALT00010002829.1
    Conserved Domains (3) summary
    cd15454
    Location:582 → 892
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    cd06376
    Location:40 → 504
    PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
    pfam07562
    Location:512 → 562
    NCD3G; Nine Cysteines Domain of family 3 GPCR

  2. XM_046903818.1 → XP_046759774.1  metabotropic glutamate receptor 8 isoform X2

  3. XM_046903819.1 → XP_046759775.1  metabotropic glutamate receptor 8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XA35

  4. XM_040652895.2 → XP_040508829.1  metabotropic glutamate receptor 8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XA35
    Conserved Domains (3) summary
    cd15454
    Location:582 → 892
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    cd06376
    Location:40 → 504
    PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
    pfam07562
    Location:512 → 562
    NCD3G; Nine Cysteines Domain of family 3 GPCR

  5. XM_040652898.2 → XP_040508832.1  metabotropic glutamate receptor 8 isoform X3

    Conserved Domains (2) summary
    cd15454
    Location:303 → 613
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    cl10011
    Location:1 → 225
    Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    21332150..21677564
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040659542.2 → XP_040515476.1  metabotropic glutamate receptor 8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XA35
    Conserved Domains (3) summary
    cd15454
    Location:582 → 892
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    cd06376
    Location:40 → 504
    PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
    pfam07562
    Location:512 → 562
    NCD3G; Nine Cysteines Domain of family 3 GPCR

  2. XM_040659547.2 → XP_040515481.1  metabotropic glutamate receptor 8 isoform X5

    Conserved Domains (3) summary
    cd06376
    Location:40 → 499
    PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
    cd14964
    Location:500 → 525
    7tm_GPCRs; TM helix 7 [structural motif]
    cl28897
    Location:492 → 594
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  3. XM_046909352.1 → XP_046765308.1  metabotropic glutamate receptor 8 isoform X2

  4. XM_046909353.1 → XP_046765309.1  metabotropic glutamate receptor 8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XA35

  5. XM_040659543.2 → XP_040515477.1  metabotropic glutamate receptor 8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XA35
    Conserved Domains (3) summary
    cd15454
    Location:582 → 892
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    cd06376
    Location:40 → 504
    PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
    pfam07562
    Location:512 → 562
    NCD3G; Nine Cysteines Domain of family 3 GPCR

  6. XM_040659546.2 → XP_040515480.1  metabotropic glutamate receptor 8 isoform X3

    Conserved Domains (2) summary
    cd15454
    Location:303 → 613
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    cl10011
    Location:1 → 225
    Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

  7. XM_040659544.1 → XP_040515478.1  metabotropic glutamate receptor 8 isoform X4

    Conserved Domains (2) summary
    cd15454
    Location:350 → 660
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    cl10011
    Location:11 → 272
    Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily
Nucleotide Protein
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