Pou5f3 POU domain class 5 transcription factor 3 [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: Pou5f3provided by CGNC
Official Full Name: POU domain class 5 transcription factor 3provided by CGNC
Primary source: CGNC:53190
See related: Ensembl:ENSGALG00010027377
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: POUV; Pou2
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Genomic context

Location:: chromosome: 17

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	17	NC_052548.1 (1135044..1138692, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	17	NC_052589.1 (542938..546585, complement)

Chromosome 17 - NC_052548.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

PouV has a critical role in DNA methylation and histone acetylation in differentiation of chick embryonic stem cells.
Title: Effect of dynamic DNA methylation and histone acetylation on cPouV expression in differentiation of chick embryonic germ cells.
Data indicate that cultured embryonic stem cells (cESCs) expressed pluripotency transcription factors, POUV, Sox-2, Nanog and Lin28 exhibited typical characteristics of pluripotency, even after six generations of rapid doubling.
Title: Four recombinant pluripotency transcriptional factors containing a protein transduction domain maintained the in vitro pluripotency of chicken embryonic stem cells.
Stduies indicate that Oct4 and Nanog genes were involved in the characterization and maintenance of the chicken pluripotency.
Title: Chicken embryonic stem cells as a non-mammalian embryonic stem cell model.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: POU domain class 5 transcription factor 3

Names: POU domain class 5 transcription factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001309372.2 → NP_001296301.2 POU domain class 5 transcription factor 3

Status: PROVISIONAL

Source sequence(s)

JAENSK010000308

UniProtKB/TrEMBL

A0A8V1A8Z6, A0A8V1AGE8

Related

ENSGALP00010040647.1, ENSGALT00010066381.1

Conserved Domains (2) summary

smart00352
Location:170 → 244

POU; Found in Pit-Oct-Unc transcription factors

smart00389
Location:264 → 320

HOX; Homeodomain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052548.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

1135044..1138692 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052589.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

542938..546585 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001110178.1: Suppressed sequence

Description

NM_001110178.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.