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NRG2 neuregulin 2 [ Gallus gallus (chicken) ]

Gene ID: 427606, updated on 13-Apr-2026
Symbol
NRG2provided by CGNC
Full Name
neuregulin 2provided by CGNC
Primary source
CGNC:611
See related
Ensembl:ENSGALG00010011853
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
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See NRG2 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
14
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 13 NC_052544.1 (405138..559030)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 13 NC_052585.1 (612875..766429)

Chromosome 13 - NC_052544.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107054478 Neighboring gene prefoldin subunit 1 Neighboring gene cysteine rich transmembrane module containing 1 Neighboring gene purine rich element binding protein A Neighboring gene uncharacterized LOC112533401 Neighboring gene pleckstrin and Sec7 domain containing 2 Neighboring gene uncharacterized LOC121106714

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in animal organ development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
pro-neuregulin-2, membrane-bound isoform

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052544.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    405138..559030
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015293545.4 → XP_015149031.1  pro-neuregulin-2, membrane-bound isoform isoform X2

    UniProtKB/TrEMBL
    A0A1D5P4M3
    Conserved Domains (2) summary
    pfam02158
    Location:362 → 721
    Neuregulin; Neuregulin family
    cd05750
    Location:147 → 238
    Ig_Pro_neuregulin; Immunoglobulin (Ig)-like domain in neuregulins

  2. XM_015293544.4 → XP_015149030.1  pro-neuregulin-2, membrane-bound isoform isoform X1

    UniProtKB/TrEMBL
    A0A1D5P4M3
    Conserved Domains (3) summary
    PHA03099
    Location:275 → 357
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    pfam02158
    Location:364 → 723
    Neuregulin; Neuregulin family
    cd05750
    Location:147 → 238
    Ig_Pro_neuregulin; Immunoglobulin (Ig)-like domain in neuregulins

  3. XM_015293546.4 → XP_015149032.1  pro-neuregulin-2, membrane-bound isoform isoform X3

    UniProtKB/TrEMBL
    A0A1D5P4M3
    Conserved Domains (3) summary
    PHA03099
    Location:275 → 349
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    pfam02158
    Location:356 → 715
    Neuregulin; Neuregulin family
    cd05750
    Location:147 → 238
    Ig_Pro_neuregulin; Immunoglobulin (Ig)-like domain in neuregulins

  4. XM_015293547.4 → XP_015149033.1  pro-neuregulin-2, membrane-bound isoform isoform X4

    UniProtKB/TrEMBL
    A0A1D5P4M3, A0A1D5PVP0
    Related
    ENSGALP00010016211.1, ENSGALT00010028304.1
    Conserved Domains (3) summary
    PHA03099
    Location:253 → 301
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    pfam02158
    Location:342 → 701
    Neuregulin; Neuregulin family
    cd05750
    Location:147 → 238
    Ig_Pro_neuregulin; Immunoglobulin (Ig)-like domain in neuregulins

  5. XM_040647040.2 → XP_040502974.1  pro-neuregulin-2, membrane-bound isoform isoform X5

    Conserved Domains (2) summary
    smart00409
    Location:43 → 124
    IG; Immunoglobulin
    cd00054
    Location:149 → 177
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052585.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    612875..766429
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040682795.2 → XP_040538729.1  pro-neuregulin-2, membrane-bound isoform isoform X2

    UniProtKB/TrEMBL
    A0A1D5P4M3
    Conserved Domains (2) summary
    pfam02158
    Location:362 → 721
    Neuregulin; Neuregulin family
    cd05750
    Location:147 → 238
    Ig_Pro_neuregulin; Immunoglobulin (Ig)-like domain in neuregulins

  2. XM_040682794.2 → XP_040538728.1  pro-neuregulin-2, membrane-bound isoform isoform X1

    UniProtKB/TrEMBL
    A0A1D5P4M3
    Conserved Domains (3) summary
    PHA03099
    Location:275 → 357
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    pfam02158
    Location:364 → 723
    Neuregulin; Neuregulin family
    cd05750
    Location:147 → 238
    Ig_Pro_neuregulin; Immunoglobulin (Ig)-like domain in neuregulins

  3. XM_040682796.2 → XP_040538730.1  pro-neuregulin-2, membrane-bound isoform isoform X3

    UniProtKB/TrEMBL
    A0A1D5P4M3
    Conserved Domains (3) summary
    PHA03099
    Location:275 → 349
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    pfam02158
    Location:356 → 715
    Neuregulin; Neuregulin family
    cd05750
    Location:147 → 238
    Ig_Pro_neuregulin; Immunoglobulin (Ig)-like domain in neuregulins

  4. XM_040682797.2 → XP_040538731.1  pro-neuregulin-2, membrane-bound isoform isoform X4

    UniProtKB/TrEMBL
    A0A1D5P4M3, A0A1D5PVP0
    Conserved Domains (3) summary
    PHA03099
    Location:253 → 301
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    pfam02158
    Location:342 → 701
    Neuregulin; Neuregulin family
    cd05750
    Location:147 → 238
    Ig_Pro_neuregulin; Immunoglobulin (Ig)-like domain in neuregulins

  5. XM_040682798.2 → XP_040538732.1  pro-neuregulin-2, membrane-bound isoform isoform X5

    Conserved Domains (2) summary
    smart00409
    Location:43 → 124
    IG; Immunoglobulin
    cd00054
    Location:149 → 177
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
Nucleotide Protein Strain
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