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pnt pointed [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42757, updated on 26-Aug-2021

Summary

Official Symbol
pntprovided by FlyBase
Official Full Name
pointedprovided by FlyBase
Primary source
FLYBASE:FBgn0003118
Locus tag
Dmel_CG17077
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
0123/09; 0608/07; 0998/12; 3520; CG17077; D-ets-2; D-Ets-2; Dmel\CG17077; DMPOINT1A; E(E2F)3D; EC3-2; EK3-2; Ets; Ets1/2; Ets2; ETS2; Ets58AB; ets94F; Ets94F; EY3-1; l(3)07825; l(3)j1B7; l(3)s118306; png; Pnt; PNT; pnt-P1; Pnt-P1; PNT-P1; pnt-P2; pnt.P1; Pnt2; pntegfr; PntP1; PNTP1; pntP2; PntP2; PNTP2; POINT; Pointed; Pointed-P1; pointed-RC; ptd
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Genomic context

See pnt in Genome Data Viewer
Location:
94E10-94E13; 3-78 cM
Exon count:
11
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (23290231..23346167, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (19115953..19171889, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene big bubble 8 Neighboring gene long non-coding RNA:CR46090 Neighboring gene DNA polymerase epsilon 255kD subunit Neighboring gene ATP synthase, coupling factor 6

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in R3/R4 cell fate commitment IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in R7 cell fate commitment IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cell dedifferentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in cell dedifferentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in determination of adult lifespan IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in determination of genital disc primordium IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in epidermal growth factor receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in epithelial cell migration, open tracheal system IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in epithelial cell proliferation involved in Malpighian tubule morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in eye-antennal disc morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in fibroblast growth factor receptor signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in fibroblast growth factor receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in imaginal disc-derived wing morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in leg disc proximal/distal pattern formation IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in lymph gland crystal cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in lymph gland plasmatocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in muscle cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of apoptotic signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in negative regulation of cardioblast cell fate specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in oenocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ommatidial rotation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in open tracheal system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in pericardial nephrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in photoreceptor cell development IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in photoreceptor cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of gene expression IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of transcription, DNA-templated IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in primary branching, open tracheal system IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of establishment of planar polarity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of neuroblast proliferation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in regulation of neuroblast proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of neurogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of neuron differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in secondary branching, open tracheal system IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in sevenless signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in sevenless signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in terminal cell fate specification, open tracheal system HMP PubMed 
involved_in trachea development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in wing disc dorsal/ventral pattern formation IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IMP
Inferred from Mutant Phenotype
more info
PubMed 

General protein information

Preferred Names
pointed
Names
CG17077-PB
CG17077-PC
CG17077-PD
CG17077-PE
Ets at 58AB
Ets protein pointed P2
Point2
Pointed2
no terminal cell clones-R
pnt-PB
pnt-PC
pnt-PD
pnt-PE
pointed P1
pointed P2
pointed-P1
pointed-P2
pointedP2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    23290231..23346167 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079737.3NP_524461.2  pointed, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524461.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P51023
    Related
    FBpp0088658, FBtr0089717
    Conserved Domains (2) summary
    cd08533
    Location:179250
    SAM_PNT-ETS-1,2; Sterile alpha motif (SAM)/Pointed domain of ETS-1,2 family
    smart00413
    Location:609693
    ETS; erythroblast transformation specific domain
  2. NM_001275943.1NP_001262872.1  pointed, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262872.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KH96
    Related
    FBpp0306621, FBtr0334554
    Conserved Domains (1) summary
    smart00413
    Location:516600
    ETS; erythroblast transformation specific domain
  3. NM_170651.4NP_732857.1  pointed, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732857.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P51023
    UniProtKB/TrEMBL
    H8F4R1
    Related
    FBpp0088657, FBtr0089716
    Conserved Domains (2) summary
    cd08533
    Location:97168
    SAM_PNT-ETS-1,2; Sterile alpha motif (SAM)/Pointed domain of ETS-1,2 family
    smart00413
    Location:527611
    ETS; erythroblast transformation specific domain
  4. NM_170070.2NP_732858.1  pointed, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732858.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P51022
    Related
    FBpp0088656, FBtr0089715
    Conserved Domains (1) summary
    smart00413
    Location:514598
    ETS; erythroblast transformation specific domain
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