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CTSL cathepsin L [ Gallus gallus (chicken) ]

Gene ID: 427466, updated on 6-Sep-2025
Official Symbol
CTSLprovided by CGNC
Official Full Name
cathepsin Lprovided by CGNC
Primary source
CGNC:53096
See related
Ensembl:ENSGALG00010010311
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
CTSV; CTSL1; CTSL2
Orthologs
human mouse all
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See CTSL in Genome Data Viewer
Location:
chromosome: Z
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (42019762..42025190)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (42019762..42025190)

Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene death-associated protein kinase 1 Neighboring gene uncharacterized LOC101750974 Neighboring gene uncharacterized LOC107052323 Neighboring gene fructose-bisphosphatase 2 Neighboring gene fructose-bisphosphatase 1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. N-terminal amino acid sequences of the heavy and light chains of chicken liver cathepsin L. Wada K, et al. FEBS Lett, 1986 Dec 15. PMID 3792553
  2. Purification and amino acid sequence of chicken liver cathepsin L. Dufour E, et al. Biochemistry, 1987 Sep 8. PMID 3676277
  3. Amino acid sequence of chicken liver cathepsin L. Wada K, et al. Eur J Biochem, 1987 Aug 17. PMID 3305012
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis involved in protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
procathepsin L
Names
cathepsin L1
cathepsin L2
cathepsin V
NP_001161481.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001168009.2 → NP_001161481.1  procathepsin L precursor

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000094
    UniProtKB/TrEMBL
    F1NYJ1
    Related
    ENSGALP00010013982.1, ENSGALT00010024635.1
    Conserved Domains (2) summary
    smart00848
    Location:44 → 102
    Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
    pfam00112
    Location:132 → 352
    Peptidase_C1; Papain family cysteine protease

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    42019762..42025190
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    42019762..42025190
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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