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DOCK8 dedicator of cytokinesis 8 [ Gallus gallus (chicken) ]

Gene ID: 427348, updated on 13-Apr-2026
Symbol
DOCK8provided by CGNC
Full Name
dedicator of cytokinesis 8provided by CGNC
Primary source
CGNC:7720
See related
Ensembl:ENSGALG00010011311
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
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Try the new Transcripts and proteins table
See DOCK8 in Genome Data Viewer
Location:
chromosome: Z
Exon count:
49
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (26224953..26308008)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (26224953..26308008)

Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121108541 Neighboring gene COBW domain containing 1 Neighboring gene uncharacterized LOC101748473 Neighboring gene uncharacterized LOC121108544 Neighboring gene uncharacterized LOC121108543 Neighboring gene KN motif and ankyrin repeat domains 1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of T cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of establishment of T cell polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell leading edge IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
dedicator of cytokinesis protein 8

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    26224953..26308008
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040656265.2 → XP_040512199.1  dedicator of cytokinesis protein 8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y436, A0A8V0Y442
    Related
    ENSGALP00010015386.1, ENSGALT00010027037.1
    Conserved Domains (2) summary
    cd08696
    Location:560 → 740
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11701
    Location:1642 → 2063
    DHR2_DOCK8; Dock Homology Region 2, a GEF domain, of Class C Dedicator of Cytokinesis 8

  2. XM_040656266.2 → XP_040512200.1  dedicator of cytokinesis protein 8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y436
    Conserved Domains (2) summary
    cd08696
    Location:560 → 740
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11701
    Location:1621 → 2042
    DHR2_DOCK8; Dock Homology Region 2, a GEF domain, of Class C Dedicator of Cytokinesis 8

  3. XM_040656267.2 → XP_040512201.1  dedicator of cytokinesis protein 8 isoform X3

    UniProtKB/TrEMBL
    A0A8V0Y436, A0A8V0YAD1
    Conserved Domains (2) summary
    cd08696
    Location:492 → 672
    C2_Dock-C; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
    cd11701
    Location:1574 → 1995
    DHR2_DOCK8; Dock Homology Region 2, a GEF domain, of Class C Dedicator of Cytokinesis 8

  4. XM_046905728.1 → XP_046761684.1  dedicator of cytokinesis protein 8 isoform X3

    UniProtKB/TrEMBL
    A0A8V0Y436, A0A8V0YAD1
    Related
    ENSGALP00010015393.1, ENSGALT00010027048.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    26224953..26308008
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046936544.1 → XP_046792500.1  dedicator of cytokinesis protein 8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y436, A0A8V0Y442

  2. XM_046936545.1 → XP_046792501.1  dedicator of cytokinesis protein 8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y436

  3. XM_046936547.1 → XP_046792503.1  dedicator of cytokinesis protein 8 isoform X3

    UniProtKB/TrEMBL
    A0A8V0Y436, A0A8V0YAD1

  4. XM_046936546.1 → XP_046792502.1  dedicator of cytokinesis protein 8 isoform X3

    UniProtKB/TrEMBL
    A0A8V0Y436, A0A8V0YAD1
Nucleotide Protein Strain
Heading Accession and Version

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