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F2R coagulation factor II thrombin receptor [ Gallus gallus (chicken) ]

Gene ID: 427212, updated on 3-Apr-2024

Summary

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Official Symbol
F2Rprovided by CGNC
Official Full Name
coagulation factor II thrombin receptorprovided by CGNC
Primary source
CGNC:11133
See related
Ensembl:ENSGALG00010010599
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Z
Exon count:
4
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (23986696..23996818, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (23986696..23996818, complement)

Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene S100 calcium binding protein Z Neighboring gene uncharacterized LOC121108266 Neighboring gene F2R like trypsin receptor 1 Neighboring gene uncharacterized LOC100857549 Neighboring gene IQ motif containing GTPase activating protein 2 Neighboring gene coagulation factor II thrombin receptor like 2 Neighboring gene synaptic vesicle glycoprotein 2C

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Thrombin and its protease-activated receptor-1 (PAR1) participate in the endothelial-mesenchymal transdifferentiation process. Archiniegas E, et al. DNA Cell Biol, 2004 Dec. PMID 15684708

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables thrombin-activated receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in blood coagulation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood coagulation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in thrombin-activated receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
proteinase-activated receptor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    23986696..23996818 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_424799.7 → XP_424799.3  proteinase-activated receptor 1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y153, A0A8V0Y7D3
    Related
    ENSGALP00010014302.1, ENSGALT00010025242.1
    Conserved Domains (1) summary
    cd15369
    Location:111 → 379
    7tmA_PAR1; protease-activated receptor 1, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_004937338.5 → XP_004937395.2  proteinase-activated receptor 1 isoform X3

    UniProtKB/TrEMBL
    A0A8V0Y153, A0A8V0YEA3
    Related
    ENSGALP00010014301.1, ENSGALT00010025237.1
    Conserved Domains (1) summary
    cd15369
    Location:92 → 360
    7tmA_PAR1; protease-activated receptor 1, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_025144768.3 → XP_025000536.2  proteinase-activated receptor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YE98
    Conserved Domains (1) summary
    cd15369
    Location:126 → 394
    7tmA_PAR1; protease-activated receptor 1, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    23986696..23996818 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046935646.1 → XP_046791602.1  proteinase-activated receptor 1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y7D3

  2. XM_046935647.1 → XP_046791603.1  proteinase-activated receptor 1 isoform X3

    UniProtKB/TrEMBL
    A0A8V0YEA3

  3. XM_046935645.1 → XP_046791601.1  proteinase-activated receptor 1 isoform X1

Nucleotide Protein
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