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IQGAP2 IQ motif containing GTPase activating protein 2 [ Gallus gallus (chicken) ]

Gene ID: 427211, updated on 20-Jun-2018

Summary

Symbol
IQGAP2provided by CGNC
Full Name
IQ motif containing GTPase activating protein 2provided by CGNC
Primary source
CGNC:11128
See related
Ensembl:ENSGALG00000014978
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs

Genomic context

See IQGAP2 in Genome Data Viewer
Location:
chromosome: Z
Exon count:
38
Annotation release Status Assembly Chr Location
104 current GRCg6a (GCF_000002315.5) Z NC_006127.5 (23461532..23577608, complement)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) Z NC_006127.4 (23461599..23577705, complement)

Chromosome Z - NC_006127.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100857549 Neighboring gene F2R like trypsin receptor 1 Neighboring gene coagulation factor II thrombin receptor Neighboring gene coagulation factor II thrombin receptor like 2 Neighboring gene synaptic vesicle glycoprotein 2C Neighboring gene POC5 centriolar protein Neighboring gene ankyrin repeat and death domain containing 1B

Genomic regions, transcripts, and products

Bibliography

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General gene information

Homology

General protein information

Preferred Names
ras GTPase-activating-like protein IQGAP2
Names
IQ motif containing GTPase activating protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001277778.1NP_001264707.1  ras GTPase-activating-like protein IQGAP2

    Status: PROVISIONAL

    Source sequence(s)
    AC192620, BU324681
    UniProtKB/TrEMBL
    A0A1D5P2U7
    Related
    ENSGALP00000046997.1, ENSGALT00000081192.1
    Conserved Domains (6) summary
    smart00015
    Location:687707
    IQ; Calmodulin-binding motif
    cd05131
    Location:9131271
    RasGAP_IQGAP2; Ras-GTPase Activating Domain of IQ motif containing GTPase activating protein 2
    smart00323
    Location:9021229
    RasGAP; GTPase-activator protein for Ras-like GTPases
    cd00014
    Location:42156
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam00612
    Location:719738
    IQ; IQ calmodulin-binding motif
    pfam03836
    Location:13651493
    RasGAP_C; RasGAP C-terminus

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCg6a Primary Assembly

Genomic

  1. NC_006127.5 Reference GRCg6a Primary Assembly

    Range
    23461532..23577608 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015277326.2XP_015132812.1  ras GTPase-activating-like protein IQGAP2 isoform X7

    UniProtKB/TrEMBL
    A0A1D5PPF6
    Related
    ENSGALP00000054755.1
    Conserved Domains (6) summary
    smart00015
    Location:538558
    IQ; Calmodulin-binding motif
    cd05131
    Location:7641122
    RasGAP_IQGAP2; Ras-GTPase Activating Domain of IQ motif containing GTPase activating protein 2
    smart00323
    Location:7531080
    RasGAP; GTPase-activator protein for Ras-like GTPases
    cd00014
    Location:42156
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam00612
    Location:570589
    IQ; IQ calmodulin-binding motif
    pfam03836
    Location:12161348
    RasGAP_C; RasGAP C-terminus
  2. XM_015277323.2XP_015132809.1  ras GTPase-activating-like protein IQGAP2 isoform X4

    Conserved Domains (6) summary
    smart00015
    Location:688708
    IQ; Calmodulin-binding motif
    cd05131
    Location:9141272
    RasGAP_IQGAP2; Ras-GTPase Activating Domain of IQ motif containing GTPase activating protein 2
    smart00323
    Location:9031230
    RasGAP; GTPase-activator protein for Ras-like GTPases
    cd00014
    Location:42156
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam00612
    Location:720739
    IQ; IQ calmodulin-binding motif
    pfam03836
    Location:13661498
    RasGAP_C; RasGAP C-terminus
  3. XM_015277321.2XP_015132807.1  ras GTPase-activating-like protein IQGAP2 isoform X2

    UniProtKB/TrEMBL
    E1C2F9
    Related
    ENSGALP00000024116.5
    Conserved Domains (6) summary
    smart00015
    Location:772792
    IQ; Calmodulin-binding motif
    cd05131
    Location:9981356
    RasGAP_IQGAP2; Ras-GTPase Activating Domain of IQ motif containing GTPase activating protein 2
    smart00323
    Location:9871314
    RasGAP; GTPase-activator protein for Ras-like GTPases
    cd00014
    Location:42156
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam00612
    Location:804823
    IQ; IQ calmodulin-binding motif
    pfam03836
    Location:14501582
    RasGAP_C; RasGAP C-terminus
  4. XM_015277325.2XP_015132811.1  ras GTPase-activating-like protein IQGAP2 isoform X6

    Conserved Domains (6) summary
    smart00015
    Location:539559
    IQ; Calmodulin-binding motif
    cd05131
    Location:7651123
    RasGAP_IQGAP2; Ras-GTPase Activating Domain of IQ motif containing GTPase activating protein 2
    smart00323
    Location:7541081
    RasGAP; GTPase-activator protein for Ras-like GTPases
    cd00014
    Location:42156
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam00612
    Location:571590
    IQ; IQ calmodulin-binding motif
    pfam03836
    Location:12171349
    RasGAP_C; RasGAP C-terminus
  5. XM_015277322.2XP_015132808.1  ras GTPase-activating-like protein IQGAP2 isoform X3

    Conserved Domains (6) summary
    smart00015
    Location:689709
    IQ; Calmodulin-binding motif
    cd05131
    Location:9151273
    RasGAP_IQGAP2; Ras-GTPase Activating Domain of IQ motif containing GTPase activating protein 2
    smart00323
    Location:9041231
    RasGAP; GTPase-activator protein for Ras-like GTPases
    cd00014
    Location:42156
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam00612
    Location:721740
    IQ; IQ calmodulin-binding motif
    pfam03836
    Location:13671499
    RasGAP_C; RasGAP C-terminus
  6. XM_015277324.2XP_015132810.1  ras GTPase-activating-like protein IQGAP2 isoform X5

    Conserved Domains (6) summary
    smart00015
    Location:623643
    IQ; Calmodulin-binding motif
    cd05131
    Location:8491207
    RasGAP_IQGAP2; Ras-GTPase Activating Domain of IQ motif containing GTPase activating protein 2
    smart00323
    Location:8381165
    RasGAP; GTPase-activator protein for Ras-like GTPases
    cd00014
    Location:42156
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam00612
    Location:655674
    IQ; IQ calmodulin-binding motif
    pfam03836
    Location:13011433
    RasGAP_C; RasGAP C-terminus
  7. XM_015277320.2XP_015132806.1  ras GTPase-activating-like protein IQGAP2 isoform X1

    Conserved Domains (6) summary
    smart00015
    Location:773793
    IQ; Calmodulin-binding motif
    cd05131
    Location:9991357
    RasGAP_IQGAP2; Ras-GTPase Activating Domain of IQ motif containing GTPase activating protein 2
    smart00323
    Location:9881315
    RasGAP; GTPase-activator protein for Ras-like GTPases
    cd00014
    Location:42156
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam00612
    Location:805824
    IQ; IQ calmodulin-binding motif
    pfam03836
    Location:14511583
    RasGAP_C; RasGAP C-terminus
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