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Cyp6d4 Cytochrome P450 6d4 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42682, updated on 18-Sep-2024

Summary

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Official Symbol
Cyp6d4provided by FlyBase
Official Full Name
Cytochrome P450 6d4provided by FlyBase
Primary source
FLYBASE:FBgn0039006
Locus tag
Dmel_CG12800
See related
AllianceGenome:FB:FBgn0039006
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
6d4; CG12800; Cyp6D4; CYP6D4; Dmel\CG12800; Hrd
Summary
Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. Is expressed in adult head; embryonic/larval midgut; spermatozoon; and yolk nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See Cyp6d4 in Genome Data Viewer
Location:
94C1-94C1; 3-76 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (22698319..22700307)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (18524041..18526029)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Nucleoporin 133kD Neighboring gene cardinal Neighboring gene Crustacean cardioactive peptide Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Clueless, a conserved Drosophila gene required for mitochondrial subcellular localization, interacts genetically with parkin. Cox RT, et al. Dis Model Mech, 2009 Sep-Oct. PMID 19638420, Free PMC Article
  2. Structural Modeling of Drosophila melanogaster Gut Cytochrome P450s and Docking Comparison of Fruit Fly Gut and Human Cytochrome P450s. Nirusimhan V, et al. Curr Drug Metab, 2022. PMID 35546755
  3. Regulation of cytochrome P450 expression in Drosophila: Genomic insights. Giraudo M, et al. Pestic Biochem Physiol, 2010 Jun 1. PMID 20582327, Free PMC Article
  4. Transcriptional regulation by CHIP/LDB complexes. Bronstein R, et al. PLoS Genet, 2010 Aug 12. PMID 20730086, Free PMC Article
  5. The Drosophila melanogaster Genetic Reference Panel. Mackay TF, et al. Nature, 2012 Feb 8. PMID 22318601, Free PMC Article

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cytochrome P450 6d4
Names
CG12800-PA
Cyp6d4-PA
cytochrome P450
NP_651082.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    22698319..22700307
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142825.4 → NP_651082.1  cytochrome P450 6d4 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651082.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VCW1
    Related
    FBpp0083697
    Conserved Domains (1) summary
    pfam00067
    Location:58 → 500
    p450; Cytochrome P450
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VCW1.1 Q9VCW1

Gene LinkOut

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