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C4 complement 4 [ Gallus gallus (chicken) ]

Gene ID: 426611, updated on 3-Dec-2024
Official Symbol
C4provided by CGNC
Official Full Name
complement 4provided by CGNC
Primary source
CGNC:52838
See related
Ensembl:ENSGALG00010003170
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
C4-2
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Location:
chromosome: 16
Exon count:
40
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 16 NC_052547.1 (2230071..2244845)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 16 NC_052588.1 (1131201..1145975)

Chromosome 16 - NC_052547.1Genomic Context describing neighboring genes Neighboring gene transporter 2, ATP binding cassette subfamily B member, MHCB region Neighboring gene major histocompatibility complex B, class I heavy chain BF2 Neighboring gene centromere protein A Neighboring gene cytochrome P450 family 21 subfamily A member 2 Neighboring gene tenascin XB

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Characterization of two avian MHC-like genes reveals an ancient origin of the CD1 family. Miller MM, et al. Proc Natl Acad Sci U S A, 2005 Jun 14. PMID 15939884, Free PMC Article
  2. Extended gene map reveals tripartite motif, C-type lectin, and Ig superfamily type genes within a subregion of the chicken MHC-B affecting infectious disease. Shiina T, et al. J Immunol, 2007 Jun 1. PMID 17513765
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
complement 4
Names
MHC-linked complement C4
complement C4

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077233.2 → NP_001070701.2  complement 4 precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000283
    UniProtKB/TrEMBL
    A0A8V0X8J3, Q076D6
    Related
    ENSGALP00010004425.1, ENSGALT00010007389.1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052547.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    2230071..2244845
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046901486.1 → XP_046757442.1  complement 4 isoform X2

    UniProtKB/TrEMBL
    Q076D6

  2. XM_046901488.1 → XP_046757444.1  complement 4 isoform X4

    UniProtKB/TrEMBL
    A0A3Q2UG72

  3. XM_046901489.1 → XP_046757445.1  complement 4 isoform X5

    UniProtKB/TrEMBL
    A0A3Q2UG72

  4. XM_046901492.1 → XP_046757448.1  complement 4 isoform X8

    UniProtKB/TrEMBL
    A0A3Q2UG72
    Related
    ENSGALP00010004428.1, ENSGALT00010007394.1

  5. XM_046901487.1 → XP_046757443.1  complement 4 isoform X3

    UniProtKB/TrEMBL
    Q076D6

  6. XM_046901491.1 → XP_046757447.1  complement 4 isoform X7

    UniProtKB/TrEMBL
    A0A3Q2UG72

  7. XM_046901485.1 → XP_046757441.1  complement 4 isoform X1

    UniProtKB/TrEMBL
    Q076D6

  8. XM_046901490.1 → XP_046757446.1  complement 4 isoform X6

    UniProtKB/TrEMBL
    Q076D6

  9. XM_046901494.1 → XP_046757450.1  complement 4 isoform X10

    UniProtKB/TrEMBL
    A0A3Q2UG72

  10. XM_046901493.1 → XP_046757449.1  complement 4 isoform X9

    UniProtKB/TrEMBL
    Q076D6

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052588.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    1131201..1145975
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046928547.1 → XP_046784503.1  complement 4 isoform X2

    UniProtKB/TrEMBL
    Q076D6

  2. XM_046928549.1 → XP_046784505.1  complement 4 isoform X4

    UniProtKB/TrEMBL
    A0A3Q2UG72

  3. XM_046928550.1 → XP_046784506.1  complement 4 isoform X5

    UniProtKB/TrEMBL
    A0A3Q2UG72

  4. XM_046928553.1 → XP_046784509.1  complement 4 isoform X8

    UniProtKB/TrEMBL
    A0A3Q2UG72

  5. XM_046928548.1 → XP_046784504.1  complement 4 isoform X3

    UniProtKB/TrEMBL
    Q076D6

  6. XM_046928552.1 → XP_046784508.1  complement 4 isoform X7

    UniProtKB/TrEMBL
    A0A3Q2UG72

  7. XM_046928546.1 → XP_046784502.1  complement 4 isoform X1

    UniProtKB/TrEMBL
    Q076D6

  8. XM_046928551.1 → XP_046784507.1  complement 4 isoform X6

    UniProtKB/TrEMBL
    Q076D6

  9. XM_046928555.1 → XP_046784511.1  complement 4 isoform X10

    UniProtKB/TrEMBL
    A0A3Q2UG72

  10. XM_046928554.1 → XP_046784510.1  complement 4 isoform X9

    UniProtKB/TrEMBL
    Q076D6
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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