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NGFR nerve growth factor receptor [ Gallus gallus (chicken) ]

Gene ID: 425805, updated on 5-Sep-2025
Symbol
NGFRprovided by CGNC
Full Name
nerve growth factor receptorprovided by CGNC
Primary source
CGNC:66496
See related
Ensembl:ENSGALG00010024218
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
TNFRSF16
Orthologs
human mouse all
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See NGFR in Genome Data Viewer
Location:
chromosome: 27
Exon count:
6
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 27 NC_052558.1 (3031019..3044987, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 27 NC_052599.1 (4162901..4176898, complement)

Chromosome 27 - NC_052558.1Genomic Context describing neighboring genes Neighboring gene speckle type BTB/POZ protein Neighboring gene uncharacterized LOC121107680 Neighboring gene neurexophilin 3 Neighboring gene uncharacterized LOC121107681 Neighboring gene G protein-activated inward rectifier potassium channel 1-like Neighboring gene membrane palmitoylated protein 3 Neighboring gene CFAP97 domain containing 1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Fates of neurotrophins after retrograde axonal transport: phosphorylation of p75NTR is a sorting signal for delayed degradation. Butowt R, et al. J Neurosci, 2009 Aug 26. PMID 19710323, Free PMC Article
  2. Role of nerve growth factor and its receptor in the morphogenesis of neural tube in early chick embryo. Bhargava S. Gen Comp Endocrinol, 2007 Aug-Sep. PMID 17418844
  3. Structure and developmental expression of the nerve growth factor receptor in the chicken central nervous system. Large TH, et al. Neuron, 1989 Feb. PMID 2560385
  4. Structure and developmental expression of the chicken NGF receptor. Heuer JG, et al. Dev Biol, 1990 Feb. PMID 2154393
  5. EphrinA6 on chick retinal axons is a key component for p75(NTR)-dependent axon repulsion and TrkB-dependent axon branching. Poopalasundaram S, et al. Mol Cell Neurosci, 2011 Jun. PMID 21463686, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data support the hypothesis that a fine-tuned interplay of ephrinA6 with p75(NTR) and TrkB is important for the guidance and branching of RGC axons.
    Title: EphrinA6 on chick retinal axons is a key component for p75(NTR)-dependent axon repulsion and TrkB-dependent axon branching.
  2. NGF signaling plays a significant role in the shaping of neural tube in chick embryos through p75(NTR)-NGF receptor.
    Title: Role of nerve growth factor and its receptor in the morphogenesis of neural tube in early chick embryo.
  3. expression 1 and 5 days after exposure to wide-band noise with two increasing levels of acoustic energy
    Title: Expression of bFGF and NGF and their receptors in chick's auditory organ following overexposure to noise.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables coreceptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables death receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nerve growth factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
tumor necrosis factor receptor superfamily member 16
Names
Low-affinity nerve growth factor receptor p75NGFR
Low-affinity nerve growth factor receptor p75NGR
NGF receptor
gp80-LNGFR
low affinity neurotrophin receptor p75NTR
low-affinity nerve growth factor receptor
nerve growth factor receptor (TNFR superfamily, member 16)
p75 ICD

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001146133.2 → NP_001139605.2  tumor necrosis factor receptor superfamily member 16 precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000364
    UniProtKB/Swiss-Prot
    P18519
    UniProtKB/TrEMBL
    A9UGK7
    Related
    ENSGALP00010036051.1, ENSGALT00010059091.1
    Conserved Domains (3) summary
    cd08311
    Location:329 → 407
    Death_p75NR; Death domain of p75 Neurotrophin Receptor
    cd13416
    Location:22 → 180
    TNFRSF16; Tumor necrosis factor receptor superfamily member 16 (TNFRSF16), also known as p75 neurotrophin receptor (p75NTR) or CD271
    pfam18422
    Location:235 → 272
    TNFR_16_TM; Tumor necrosis factor receptor member 16 trans-membrane domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052558.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    3031019..3044987 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052599.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    4162901..4176898 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P18519.1 GenPept UniProtKB/Swiss-Prot:P18519

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials