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MHCY2B2 major histocompatibility complex Y, class II beta 2 [ Gallus gallus (chicken) ]

Gene ID: 425256, updated on 21-Dec-2022

Summary

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Official Symbol
MHCY2B2provided by CGNC
Official Full Name
major histocompatibility complex Y, class II beta 2provided by CGNC
Primary source
CGNC:52398
See related
Ensembl:ENSGALG00010002386
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
BLB3; RJF.Contig1.LOC12.MHCY2B2
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Genomic context

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See MHCY2B2 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
6
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 16 NC_052547.1 (1662533..1668757)

Chromosome 16 - NC_052547.1Genomic Context describing neighboring genes Neighboring gene major histocompatibility complex Y, class I heavy chain 15 Neighboring gene C-type lectin domain family 2 member I-like Neighboring gene major histocompatibility complex Y, class I heavy chain 4 Neighboring gene RNA, 18S ribosomal 19 Neighboring gene zinc finger protein OZF-like Neighboring gene MHCY region zinc finger protein 2 Neighboring gene c-type lectin like 3, MHCY region pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_052547.1 Chromosome 16 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Isolation of chicken major histocompatibility complex class II (B-L) beta chain sequences: comparison with mammalian beta chains and expression in lymphoid organs. Bourlet Y, et al. EMBO J, 1988 Apr. PMID 2841107, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
class II histocompatibility antigen, B-L beta chain
Names
B-L beta chain
Major histocompatibility complex class II beta chain BLB3, (similar to HLA class II, D beta chain)
Y-Lb III
major histocompatibility complex-Y, class II beta chain, 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001393722.2 → NP_001380651.1  class II histocompatibility antigen, B-L beta chain

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000280
    Conserved Domains (2) summary
    pfam00969
    Location:67 → 140
    MHC_II_beta; Class II histocompatibility antigen, beta domain
    cd05766
    Location:146 → 241
    IgC1_MHC_II_beta; Class II major histocompatibility complex (MHC) beta chain immunoglobulin domain; member of the C1-set of Ig superfamily (IgSF) domains

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052547.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    1662533..1668757
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015302127.3 → XP_015157613.1  class II histocompatibility antigen, B-L beta chain isoform X1

    Conserved Domains (2) summary
    cd05766
    Location:149 → 242
    IgC_MHC_II_beta; Class II major histocompatibility complex (MHC) beta chain immunoglobulin domain
    pfam00969
    Location:67 → 140
    MHC_II_beta; Class II histocompatibility antigen, beta domain

  2. XM_040648594.1 → XP_040504528.1  class II histocompatibility antigen, B-L beta chain isoform X2

    Conserved Domains (3) summary
    smart00921
    Location:67 → 137
    MHC_II_beta; Class II histocompatibility antigen, beta domain
    smart00407
    Location:167 → 235
    IGc1; Immunoglobulin C-Type
    cd00096
    Location:178 → 183
    Ig; Ig strand C [structural motif]

  3. XM_040648595.1 → XP_040504529.1  class II histocompatibility antigen, B-L beta chain isoform X3

    Conserved Domains (3) summary
    smart00921
    Location:67 → 137
    MHC_II_beta; Class II histocompatibility antigen, beta domain
    smart00407
    Location:167 → 235
    IGc1; Immunoglobulin C-Type
    cd00096
    Location:178 → 183
    Ig; Ig strand C [structural motif]

  4. XM_040648596.1 → XP_040504530.1  class II histocompatibility antigen, B-L beta chain isoform X4

    UniProtKB/TrEMBL
    A0A8V0XG27
    Related
    ENSGALP00010003308.1, ENSGALT00010005469.1
    Conserved Domains (3) summary
    smart00921
    Location:67 → 137
    MHC_II_beta; Class II histocompatibility antigen, beta domain
    smart00407
    Location:167 → 235
    IGc1; Immunoglobulin C-Type
    cd00096
    Location:178 → 183
    Ig; Ig strand C [structural motif]

  5. XM_025155931.3 → XP_025011699.1  class II histocompatibility antigen, B-L beta chain isoform X5

    UniProtKB/TrEMBL
    A0A8V0XF96
    Related
    ENSGALP00010003310.1, ENSGALT00010005471.1
    Conserved Domains (2) summary
    cd05766
    Location:149 → 242
    IgC_MHC_II_beta; Class II major histocompatibility complex (MHC) beta chain immunoglobulin domain
    pfam00969
    Location:67 → 140
    MHC_II_beta; Class II histocompatibility antigen, beta domain

RNA

  1. XR_003077950.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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