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Rab1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42524, updated on 19-Oct-2021

Summary

Official Symbol
Rab1provided by FlyBase
Primary source
FLYBASE:FBgn0285937
Locus tag
Dmel_CG3320
Gene type
protein coding
RNA name
Rab1
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
AAF55873; CG3320; dar6; Dar6; Dm Rab1; Dmel\CG3320; DmRab1; drab1; dRab1; DRab1; DRAB1; O18332; omt; rab1; Rab1a; RAB1a
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Genomic context

See Rab1 in Genome Data Viewer
Location:
93D2-93D2; 3-71 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (21266029..21269060, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (17091751..17094782, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ETHR Neighboring gene antisense RNA:CR45798 Neighboring gene Adaptor Protein complex 2, sigma subunit Neighboring gene uncharacterized protein Neighboring gene Isopentenyl-diphosphate delta isomerase

Genomic regions, transcripts, and products

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the Rab1 gene: The Rab1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, mouse, rat, chicken, zebrafish, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables GTPase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables GTPase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables Golgi transport complex binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in Rab protein signal transduction ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in anterograde axonal transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in carbohydrate homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport TAS
Traceable Author Statement
more info
PubMed 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in male meiosis cytokinesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mitotic cytokinesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of viral entry into host cell HMP PubMed 
involved_in positive regulation of dendrite morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of insulin secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of synapse pruning IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein localization to Golgi apparatus IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein localization to cleavage furrow IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein secretion IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in protein secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in cleavage furrow IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in cytoplasm HDA PubMed 
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum exit site IDA
Inferred from Direct Assay
more info
PubMed 
located_in neuronal cell body HDA PubMed 
located_in vesicle ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
Rab1
Names
CG3320-PA
Rab-protein 1
Rab1-PA
dendritic arbor reduction 6
omelette

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    21266029..21269060 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_169953.3NP_732610.1  Rab1 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732610.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O18332
    Related
    FBpp0083503, FBtr0084104
    Conserved Domains (1) summary
    cd01869
    Location:10175
    Rab1_Ypt1; Rab GTPase family 1 includes the yeast homolog Ypt1
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