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STAM2 signal transducing adaptor molecule 2 [ Gallus gallus (chicken) ]

Gene ID: 424317, updated on 13-Apr-2026
Symbol
STAM2provided by CGNC
Full Name
signal transducing adaptor molecule 2provided by CGNC
Primary source
CGNC:9498
See related
Ensembl:ENSGALG00010010287
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
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Try the new Transcripts and proteins table
See STAM2 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
15
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 7 NC_052538.1 (35014653..35038393, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 7 NC_052579.1 (34933940..34957670, complement)

Chromosome 7 - NC_052538.1Genomic Context describing neighboring genes Neighboring gene calcium voltage-gated channel auxiliary subunit beta 4 Neighboring gene uncharacterized LOC101748276 Neighboring gene uncharacterized LOC101748222 Neighboring gene uncharacterized LOC121111348 Neighboring gene formin like 2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. EAST, a novel EGF receptor substrate, associates with focal adhesions and actin fibers. Lohi O, et al. FEBS Lett, 1998 Oct 9. PMID 9801161
  2. Src phosphorylates EAST, a novel EGF receptor-associated protein. Lohi O, et al. FEBS Lett, 1998 Aug 7. PMID 9720929
  3. EAST, an epidermal growth factor receptor- and Eps15-associated protein with Src homology 3 and tyrosine-based activation motif domains. Lohi O, et al. J Biol Chem, 1998 Aug 14. PMID 9694904
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endocytic vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
signal transducing adapter molecule 2
Names
EAST protein
STAM-2
epidermal growth factor receptor-associated protein with SH3 and TAM domain
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001396689.1 → NP_001383618.1  signal transducing adapter molecule 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000236
    UniProtKB/TrEMBL
    A0A8V0Y4Q6
    Conserved Domains (3) summary
    smart00726
    Location:171 → 189
    UIM; Ubiquitin-interacting motif
    cd11963
    Location:209 → 265
    SH3_STAM2; Src homology 3 domain of Signal Transducing Adaptor Molecule 2
    cd16999
    Location:9 → 152
    VHS_STAM2; VHS (Vps27/Hrs/STAM) domain of Signal Transducing Adapter Molecule 2

  2. NM_001396690.1 → NP_001383619.1  signal transducing adapter molecule 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000236
    UniProtKB/TrEMBL
    A0A8V0Y4Q6
    Related
    ENSGALP00010013940.1, ENSGALT00010024569.1
    Conserved Domains (3) summary
    smart00726
    Location:165 → 183
    UIM; Ubiquitin-interacting motif
    cd11963
    Location:203 → 259
    SH3_STAM2; Src homology 3 domain of Signal Transducing Adaptor Molecule 2
    cd16999
    Location:9 → 146
    VHS_STAM2; VHS (Vps27/Hrs/STAM) domain of Signal Transducing Adapter Molecule 2

  3. NM_001396691.1 → NP_001383620.1  signal transducing adapter molecule 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000236
    Conserved Domains (3) summary
    smart00726
    Location:54 → 72
    UIM; Ubiquitin-interacting motif
    cd11963
    Location:92 → 148
    SH3_STAM2; Src homology 3 domain of Signal Transducing Adaptor Molecule 2
    cl02544
    Location:1 → 35
    VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052538.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    35014653..35038393 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046943657.1 → XP_046799613.1  signal transducing adapter molecule 2 isoform X2

  2. XM_046943655.1 → XP_046799611.1  signal transducing adapter molecule 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y4Q6

  3. XM_046943658.1 → XP_046799614.1  signal transducing adapter molecule 2 isoform X2

  4. XM_046943656.1 → XP_046799612.1  signal transducing adapter molecule 2 isoform X2

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052579.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    34933940..34957670 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046921565.1 → XP_046777521.1  signal transducing adapter molecule 2 isoform X2

  2. XM_046921562.1 → XP_046777518.1  signal transducing adapter molecule 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y4Q6

  3. XM_046921566.1 → XP_046777522.1  signal transducing adapter molecule 2 isoform X2

  4. XM_046921564.1 → XP_046777520.1  signal transducing adapter molecule 2 isoform X2

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O93436.1 GenPept UniProtKB/Swiss-Prot:O93436

Gene LinkOut

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