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PRKAG3 protein kinase AMP-activated non-catalytic subunit gamma 3 [ Gallus gallus (chicken) ]

Gene ID: 424208, updated on 16-Jun-2026
Symbol
PRKAG3provided by CGNC
Full Name
protein kinase AMP-activated non-catalytic subunit gamma 3provided by CGNC
Primary source
CGNC:8637
See related
Ensembl:ENSGALG00010021564
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
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Try the new Transcripts and proteins table
See PRKAG3 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
12
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 7 NC_052538.1 (22045347..22049491, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 7 NC_052579.1 (21965143..21969287, complement)

Chromosome 7 - NC_052538.1Genomic Context describing neighboring genes Neighboring gene transfer RNA valine (anticodon GAC) Neighboring gene Wnt family member 10A Neighboring gene Wnt family member 6 Neighboring gene cytochrome P450 family 27 subfamily A member 1 Neighboring gene tubulin tyrosine ligase like 4 Neighboring gene serine/threonine kinase 36

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. An SNP in Exon 11 of Chicken 5'-AMP-Activated Protein Kinase Gamma 3 Subunit Gene was Associated with Meat Water Holding Capacity. Yang Y, et al. Anim Biotechnol, 2016. PMID 26597656
  2. Identification of single-nucleotide polymorphisms in 5' end and exons of the PRKAG3 gene in Hubbard White broiler, Leghorn layer, and three Chinese indigenous chicken breeds. Zhao CJ, et al. J Anim Breed Genet, 2006 Oct. PMID 16965409
  3. Association of AMPK subunit gene polymorphisms with growth, feed intake, and feed efficiency in meat-type chickens. Jin S, et al. Poult Sci, 2016 Jul 1. PMID 27143764
  4. Characterization of the AMP-activated protein kinase pathway in chickens. Proszkowiec-Weglarz M, et al. Comp Biochem Physiol B Biochem Mol Biol, 2006 Jan. PMID 16343965

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The findings provide important evidence for association of AMPK subunits PRKAB1, PRKAG2, and PRKAG3 single nucleotide polymorphisms with body weight, feed intake, and feed efficiency that may be applied in meat-type chicken breeding programs.
    Title: Association of AMPK subunit gene polymorphisms with growth, feed intake, and feed efficiency in meat-type chickens.
  2. Association between the genotypes of chicken PRKAG3 and chicken meat quality traits were studied.
    Title: An SNP in Exon 11 of Chicken 5'-AMP-Activated Protein Kinase Gamma 3 Subunit Gene was Associated with Meat Water Holding Capacity.
Submit: New GeneRIF Correction

Homology

Preferred Names
5'-AMP-activated protein kinase subunit gamma-3
Names
5'-AMP-activated protein kinase gamma-3 non-catalytic subunit long form
AMP-activated protein kinase gamma subunit
protein kinase non-catalytic gamma subunit
protein kinase, AMP-activated, gamma 3 non-catalytic subunit

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001031258.3 → NP_001026429.2  5'-AMP-activated protein kinase subunit gamma-3

    See identical proteins and their annotated locations for NP_001026429.2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000236
    UniProtKB/TrEMBL
    A0A8V0ZIT4, A0A8V0ZKJ7, Q4JK38
    Related
    ENSGALP00010031276.1, ENSGALT00010052343.1
    Conserved Domains (3) summary
    COG0517
    Location:246 → 363
    CBS; CBS domain [Signal transduction mechanisms]
    cd04618
    Location:91 → 219
    CBS_pair_5; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...
    cd04641
    Location:246 → 365
    CBS_pair_28; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052538.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    22045347..22049491 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040703450.2 → XP_040559384.1  5'-AMP-activated protein kinase subunit gamma-3 isoform X6

    Conserved Domains (2) summary
    cd04618
    Location:9 → 171
    CBS_euAMPK_gamma-like_repeat1; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains found in AMP-activated protein kinase gamma-like proteins, repeat 1
    cd04641
    Location:197 → 320
    CBS_euAMPK_gamma-like_repeat2; CBS pair domain found in 5'-AMP (adenosine monophosphate)-activated protein kinase

  2. XM_040703447.2 → XP_040559381.1  5'-AMP-activated protein kinase subunit gamma-3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZIT4
    Conserved Domains (2) summary
    cd04618
    Location:82 → 244
    CBS_euAMPK_gamma-like_repeat1; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains found in AMP-activated protein kinase gamma-like proteins, repeat 1
    cd04641
    Location:270 → 393
    CBS_euAMPK_gamma-like_repeat2; CBS pair domain found in 5'-AMP (adenosine monophosphate)-activated protein kinase

  3. XM_015289796.4 → XP_015145282.2  5'-AMP-activated protein kinase subunit gamma-3 isoform X5

    UniProtKB/TrEMBL
    A0A8V0ZIT4, Q4JK39
    Related
    ENSGALP00010031265.1, ENSGALT00010052327.1
    Conserved Domains (2) summary
    cd04618
    Location:86 → 222
    CBS_euAMPK_gamma-like_repeat1; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains found in AMP-activated protein kinase gamma-like proteins, repeat 1
    cd04641
    Location:248 → 371
    CBS_euAMPK_gamma-like_repeat2; CBS pair domain found in 5'-AMP (adenosine monophosphate)-activated protein kinase

  4. XM_040703446.2 → XP_040559380.1  5'-AMP-activated protein kinase subunit gamma-3 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZIT4
    Conserved Domains (2) summary
    cd04618
    Location:86 → 248
    CBS_euAMPK_gamma-like_repeat1; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains found in AMP-activated protein kinase gamma-like proteins, repeat 1
    cd04641
    Location:274 → 397
    CBS_euAMPK_gamma-like_repeat2; CBS pair domain found in 5'-AMP (adenosine monophosphate)-activated protein kinase

  5. XM_040703449.2 → XP_040559383.1  5'-AMP-activated protein kinase subunit gamma-3 isoform X4

    UniProtKB/TrEMBL
    A0A8V0ZIT4
    Conserved Domains (2) summary
    cd04618
    Location:64 → 226
    CBS_euAMPK_gamma-like_repeat1; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains found in AMP-activated protein kinase gamma-like proteins, repeat 1
    cd04641
    Location:252 → 375
    CBS_euAMPK_gamma-like_repeat2; CBS pair domain found in 5'-AMP (adenosine monophosphate)-activated protein kinase

  6. XM_040703448.2 → XP_040559382.1  5'-AMP-activated protein kinase subunit gamma-3 isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZIT4
    Conserved Domains (2) summary
    cd04618
    Location:68 → 230
    CBS_euAMPK_gamma-like_repeat1; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains found in AMP-activated protein kinase gamma-like proteins, repeat 1
    cd04641
    Location:256 → 379
    CBS_euAMPK_gamma-like_repeat2; CBS pair domain found in 5'-AMP (adenosine monophosphate)-activated protein kinase

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052579.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    21965143..21969287 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046921428.1 → XP_046777384.1  5'-AMP-activated protein kinase subunit gamma-3 isoform X6

  2. XM_046921424.1 → XP_046777380.1  5'-AMP-activated protein kinase subunit gamma-3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZIT4

  3. XM_046921427.1 → XP_046777383.1  5'-AMP-activated protein kinase subunit gamma-3 isoform X5

    UniProtKB/TrEMBL
    A0A8V0ZIT4, Q4JK39

  4. XM_046921423.1 → XP_046777379.1  5'-AMP-activated protein kinase subunit gamma-3 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZIT4

  5. XM_046921426.1 → XP_046777382.1  5'-AMP-activated protein kinase subunit gamma-3 isoform X4

    UniProtKB/TrEMBL
    A0A8V0ZIT4

  6. XM_046921425.1 → XP_046777381.1  5'-AMP-activated protein kinase subunit gamma-3 isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZIT4
Nucleotide Protein Strain
Heading Accession and Version

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