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EMX2 empty spiracles homeobox 2 [ Gallus gallus (chicken) ]

Gene ID: 423923, updated on 13-Apr-2026
Symbol
EMX2provided by CGNC
Full Name
empty spiracles homeobox 2provided by CGNC
Primary source
CGNC:7069
See related
Ensembl:ENSGALG00010001948
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
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See EMX2 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
4
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 6 NC_052537.1 (30062195..30069586)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 6 NC_052578.1 (29951971..29959435)

Chromosome 6 - NC_052537.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101747677 Neighboring gene uncharacterized LOC101747620 Neighboring gene uncharacterized LOC107053726 Neighboring gene uncharacterized LOC121111170 Neighboring gene uncharacterized LOC121111171

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. EMX2 activates slow myosin heavy chain 2 gene expression in embryonic muscle fibers. Hatch K, et al. Mech Dev, 2017 Oct. PMID 28673691, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. EMX2 activates MyHC2 gene expression in embryonic muscle fibers.
    Title: EMX2 activates slow myosin heavy chain 2 gene expression in embryonic muscle fibers.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in brain development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in central nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
homeobox protein EMX2
Names
empty spiracles homolog 2

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052537.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    30062195..30069586
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025152057.3 → XP_025007825.1  homeobox protein EMX2 isoform X1

    UniProtKB/TrEMBL
    E1BT91
    Related
    ENSGALP00010002703.1, ENSGALT00010004447.1
    Conserved Domains (1) summary
    pfam00046
    Location:153 → 206
    Homeobox; Homeobox domain

  2. XM_025152058.3 → XP_025007826.1  homeobox protein EMX2 isoform X2

  3. XM_015288919.4 → XP_015144405.2  homeobox protein EMX2 isoform X3

    UniProtKB/TrEMBL
    A0A8V0XAX0
    Related
    ENSGALP00010002701.1, ENSGALT00010004444.1
    Conserved Domains (1) summary
    cd00086
    Location:150 → 208
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052578.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    29951971..29959435
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040674825.2 → XP_040530759.1  homeobox protein EMX2 isoform X1

    UniProtKB/TrEMBL
    E1BT91
    Conserved Domains (1) summary
    pfam00046
    Location:153 → 206
    Homeobox; Homeobox domain

  2. XM_040674826.2 → XP_040530760.1  homeobox protein EMX2 isoform X2

Nucleotide Protein Strain
Heading Accession and Version

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Molecular Biology Databases
Research Materials