IFIT5 interferon induced protein with tetratricopeptide repeats 5 [Gallus gallus (chicken)] - Gene

Summary

Symbol: IFIT5provided by CGNC
Full Name: interferon induced protein with tetratricopeptide repeats 5provided by CGNC
Primary source: CGNC:52052
See related: Ensembl:ENSGALG00010018016
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
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Genomic context

Location:: chromosome: 6

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	6	NC_052537.1 (20119110..20122822)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	6	NC_052578.1 (20106049..20109761)

Chromosome 6 - NC_052537.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

IFIT5 antagonizes replication of RNA viruses.
Title: Chicken Interferon-induced Protein with Tetratricopeptide Repeats 5 Antagonizes Replication of RNA Viruses.
this study shows that chickens expressing IFIT5 ameliorate clinical outcome and pathology of highly pathogenic Avian Influenza and velogenic Newcastle Disease viruses
Title: Chickens Expressing IFIT5 Ameliorate Clinical Outcome and Pathology of Highly Pathogenic Avian Influenza and Velogenic Newcastle Disease Viruses.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in defense response to virus	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: interferon-induced protein with tetratricopeptide repeats 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001320422.2 → NP_001307351.1 interferon-induced protein with tetratricopeptide repeats 5

Status: PROVISIONAL

Source sequence(s)

JAENSK010000231

UniProtKB/TrEMBL

A0A125RM76, A0A126TRG3

Related

ENSGALP00010025900.1, ENSGALT00010043547.1

Conserved Domains (3) summary

PRK02603
Location:386 → 461

PRK02603; photosystem I assembly protein Ycf3; Provisional

TIGR02917
Location:67 → 360

PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein

sd00006
Location:249 → 277

TPR; TPR repeat [structural motif]