U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ACTA2 actin, alpha 2, smooth muscle, aorta [ Gallus gallus (chicken) ]

Gene ID: 423787, updated on 5-Aug-2026
Symbol
ACTA2provided by CGNC
Full Name
actin, alpha 2, smooth muscle, aortaprovided by CGNC
Primary source
CGNC:52051
See related
Ensembl:ENSGALG00010022071
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
asma
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See ACTA2 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
19
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 6 NC_052537.1 (19993995..20050197, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 6 NC_052578.1 (19980916..20037141, complement)

Chromosome 6 - NC_052537.1Genomic Context describing neighboring genes Neighboring gene lipase member M-like 4 Neighboring gene STAM binding protein like 1 Neighboring gene Fas cell surface death receptor Neighboring gene cholesterol 25-hydroxylase Neighboring gene lipase A, lysosomal acid type

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Increased arterial load alters aortic structural and functional properties during embryogenesis. Lucitti JL, et al. Am J Physiol Heart Circ Physiol, 2006 Oct. PMID 16648183
  2. Structure and complete nucleotide sequence of the chicken alpha-smooth muscle (aortic) actin gene. An actin gene which produces multiple messenger RNAs. Carroll SL, et al. J Biol Chem, 1986 Jul 5. PMID 3013870
  3. Pericytes in the mature chorioallantoic membrane capillary plexus contain desmin and alpha-smooth muscle actin: relevance for non-sprouting angiogenesis. Kurz H, et al. Histochem Cell Biol, 2008 Nov. PMID 18688635
  4. Antisense oligodeoxynucleotide complementary to smooth muscle alpha-actin inhibits endothelial-mesenchymal transformation during chick cardiogenesis. Nakajima Y, et al. Dev Dyn, 1999 Dec. PMID 10633868
  5. Isolation and characterization of six different chicken actin genes. Chang KS, et al. Mol Cell Biol, 1984 Nov. PMID 6513927, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The distribution of laminin and alphaSMA in the testis and epididymis might point out to their roles in the male reproduction.
    Title: Comparative expression of laminin and smooth muscle actin in the testis and epididymis of poultry and rabbit.
  2. Pericytes in the mature chorioallantoic membrane capillary plexus contain desmin and alpha-smooth muscle actin: relevance for non-sprouting angiogenesis.
    Title: Pericytes in the mature chorioallantoic membrane capillary plexus contain desmin and alpha-smooth muscle actin: relevance for non-sprouting angiogenesis.
  3. Thus the embryonic dorsal aorta is sensitive to increased arterial load and adapts by altering its material properties via changes in collagen and alpha-actin content.
    Title: Increased arterial load alters aortic structural and functional properties during embryogenesis.
Submit: New GeneRIF Correction

Markers

Homology

Preferred Names
actin, aortic smooth muscle
Names
alpha-actin

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001031229.2 → NP_001026400.2  actin, aortic smooth muscle

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000231
    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476
    Related
    ENSGALP00010032334.1, ENSGALT00010053682.1
    Conserved Domains (1) summary
    PTZ00281
    Location:3 → 377
    PTZ00281; actin; Provisional

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052537.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    19993995..20050197 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015288392.4 → XP_015143878.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476
    Conserved Domains (1) summary
    PTZ00281
    Location:3 → 377
    PTZ00281; actin; Provisional

  2. XM_046942894.1 → XP_046798850.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476

  3. XM_046942896.1 → XP_046798852.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476

  4. XM_046942898.1 → XP_046798854.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476

  5. XM_046942897.1 → XP_046798853.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476

  6. XM_046942902.1 → XP_046798858.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476

  7. XM_046942901.1 → XP_046798857.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476

  8. XM_046942899.1 → XP_046798855.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476

  9. XM_046942900.1 → XP_046798856.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476

  10. XM_046942895.1 → XP_046798851.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052578.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    19980916..20037141 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046920238.1 → XP_046776194.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476

  2. XM_046920234.1 → XP_046776190.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476

  3. XM_046920237.1 → XP_046776193.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476

  4. XM_046920240.1 → XP_046776196.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476

  5. XM_046920239.1 → XP_046776195.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476

  6. XM_046920244.1 → XP_046776200.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476

  7. XM_046920243.1 → XP_046776199.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476

  8. XM_046920242.1 → XP_046776198.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476

  9. XM_046920233.1 → XP_046776189.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476

  10. XM_046920241.1 → XP_046776197.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476

  11. XM_046920236.1 → XP_046776192.1  actin, aortic smooth muscle isoform X1

    UniProtKB/Swiss-Prot
    P08023
    UniProtKB/TrEMBL
    A0A1I7Q414, A0A1L1RXB8, F1P476
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P08023.2 GenPept UniProtKB/Swiss-Prot:P08023

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials