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ABCG2 ATP binding cassette subfamily G member 2 [ Gallus gallus (chicken) ]

Gene ID: 423767, updated on 13-Apr-2026
Official Symbol
ABCG2provided by CGNC
Official Full Name
ATP binding cassette subfamily G member 2provided by CGNC
Primary source
CGNC:4322
See related
Ensembl:ENSGALG00010020622
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
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Try the new Transcripts and proteins table
See ABCG2 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
18
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 6 NC_052537.1 (18307033..18324885)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 6 NC_052578.1 (18293024..18310901)

Chromosome 6 - NC_052537.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124418051 Neighboring gene stearoyl-CoA desaturase Neighboring gene polycystin 2 like 1, transient receptor potential cation channel Neighboring gene uncharacterized LOC112532676 Neighboring gene biogenesis of lysosomal organelles complex 1 subunit 2 Neighboring gene uncharacterized LOC124418053 Neighboring gene cytochrome P450 family 2 subfamily C member 23b

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Identification of Functional Transcriptional Binding Sites within Chicken Abcg2 Gene Promoter and Screening Its Regulators. Zhang Y, et al. Genes (Basel), 2020 Feb 10. PMID 32050731, Free PMC Article
  2. Effect of colibacillosis or coccidiosis on expression of breast cancer resistance protein in small intestine and liver of chickens. Su L, et al. J Vet Pharmacol Ther, 2014 Feb. PMID 23531049
  3. Uric acid transporters BCRP and MRP4 involved in chickens uric acid excretion. Ding X, et al. BMC Vet Res, 2019 May 30. PMID 31146764, Free PMC Article
  4. Potential pharmacokinetic effect of rifampicin on enrofloxacin in broilers: Roles of P-glycoprotein and BCRP induction by rifampicin. Guo M, et al. Poult Sci, 2016 Sep 1. PMID 27118859
  5. Quantitative expression of candidate genes affecting eggshell color. Zheng C, et al. Anim Sci J, 2014 May. PMID 24612318

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Identification of Functional Transcriptional Binding Sites within Chicken Abcg2 Gene Promoter and Screening Its Regulators.
    Title: Identification of Functional Transcriptional Binding Sites within Chicken Abcg2 Gene Promoter and Screening Its Regulators.
  2. results show that BCRP and MRP4 participate in renal and intestinal uric acid excretion in chickens and that BCRP is positively related to MRP4 mRNA expression
    Title: Uric acid transporters BCRP and MRP4 involved in chickens uric acid excretion.
  3. This study shows that rifampicin up-regulated the small intestinal level of P-gp and BCRP and suggests that P-gp and BCRP are key factors that affected pharmacokinetic behavior of orally administered enrofloxacin by limiting its absorption from the intestine in broilers.
    Title: Potential pharmacokinetic effect of rifampicin on enrofloxacin in broilers: Roles of P-glycoprotein and BCRP induction by rifampicin.
  4. High-level expression of BCRP, HRG1 and FLVCR were associated with brown, white and generally lighter eggshell colors, respectively
    Title: Quantitative expression of candidate genes affecting eggshell color.
  5. The results indicate that coccidiosis or colibacillosis infection inhibits BCRP expression in chickens, which may consequently influence drug distribution and therapeutic efficacy.
    Title: Effect of colibacillosis or coccidiosis on expression of breast cancer resistance protein in small intestine and liver of chickens.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
broad substrate specificity ATP-binding cassette transporter ABCG2
Names
ATP binding cassette subfamily G member 2 (Junior blood group)
ATP-binding cassette sub-family G member 2
ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
NP_001315419.2
NP_001384181.1
NP_001384182.1
NP_001384183.1
NP_001384184.1
NP_001384185.1
NP_001384186.1
NP_001384187.1
XP_015143936.2
XP_015143937.2
XP_046776170.1
XP_046776171.1
XP_046776172.1
XP_046798837.1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001328490.2 → NP_001315419.2  broad substrate specificity ATP-binding cassette transporter ABCG2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000231
    UniProtKB/TrEMBL
    A0A8V0ZF91, A0A8V0ZLB3
    Conserved Domains (1) summary
    TIGR00955
    Location:72 → 695
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein

  2. NM_001397252.1 → NP_001384181.1  broad substrate specificity ATP-binding cassette transporter ABCG2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000231
    UniProtKB/TrEMBL
    A0A8V0ZF91, A0A8V0ZLB3
    Related
    ENSGALP00010029415.1, ENSGALT00010049780.1
    Conserved Domains (1) summary
    TIGR00955
    Location:72 → 695
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein

  3. NM_001397253.1 → NP_001384182.1  broad substrate specificity ATP-binding cassette transporter ABCG2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000231
    UniProtKB/TrEMBL
    A0A8V0ZF91, A0A8V0ZLB3
    Conserved Domains (1) summary
    TIGR00955
    Location:72 → 695
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein

  4. NM_001397254.1 → NP_001384183.1  broad substrate specificity ATP-binding cassette transporter ABCG2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000231
    UniProtKB/TrEMBL
    A0A8V0ZF91, A0A8V0ZLB3
    Conserved Domains (1) summary
    TIGR00955
    Location:72 → 695
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein

  5. NM_001397255.1 → NP_001384184.1  broad substrate specificity ATP-binding cassette transporter ABCG2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000231
    UniProtKB/TrEMBL
    A0A8V0ZF91, A0A8V0ZLB3
    Conserved Domains (1) summary
    TIGR00955
    Location:72 → 695
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein

  6. NM_001397256.1 → NP_001384185.1  broad substrate specificity ATP-binding cassette transporter ABCG2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000231
    UniProtKB/TrEMBL
    A0A8V0ZF91, A0A8V0ZLB3
    Conserved Domains (1) summary
    TIGR00955
    Location:72 → 695
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein

  7. NM_001397257.1 → NP_001384186.1  broad substrate specificity ATP-binding cassette transporter ABCG2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000231
    UniProtKB/TrEMBL
    A0A8V0ZF91, A0A8V0ZLB3
    Conserved Domains (1) summary
    TIGR00955
    Location:72 → 695
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein

  8. NM_001397258.1 → NP_001384187.1  broad substrate specificity ATP-binding cassette transporter ABCG2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000231
    UniProtKB/TrEMBL
    A0A8V0ZF91, A0A8V0ZLB3
    Related
    ENSGALP00010029414.1, ENSGALT00010049779.1
    Conserved Domains (1) summary
    TIGR00955
    Location:72 → 695
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052537.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    18307033..18324885
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015288451.4 → XP_015143937.2  broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZF91, A0A8V0ZLB3
    Conserved Domains (1) summary
    TIGR00955
    Location:72 → 695
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein

  2. XM_015288450.4 → XP_015143936.2  broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZF91, A0A8V0ZLB3
    Conserved Domains (1) summary
    TIGR00955
    Location:72 → 695
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein

  3. XM_046942881.1 → XP_046798837.1  broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZLB3

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052578.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    18293024..18310901
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046920215.1 → XP_046776171.1  broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X1

    UniProtKB/TrEMBL
    A0A173GYX1, A0A1D5PMT4, A0A8V0ZLB3, E1C5B1

  2. XM_046920214.1 → XP_046776170.1  broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X1

    UniProtKB/TrEMBL
    A0A173GYX1, A0A1D5PMT4, A0A8V0ZLB3, E1C5B1

  3. XM_046920216.1 → XP_046776172.1  broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZLB3
Nucleotide Protein
Heading Accession and Version

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