CDKN3 cyclin dependent kinase inhibitor 3 [Gallus gallus (chicken)] - Gene

Summary

Symbol: CDKN3provided by CGNC
Full Name: cyclin dependent kinase inhibitor 3provided by CGNC
Primary source: CGNC:9281
See related: Ensembl:ENSGALG00010018932
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: all
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Genomic context

Location:: chromosome: 5

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	5	NC_052536.1 (56070550..56077439, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	5	NC_052577.1 (56111847..56118714, complement)

Chromosome 5 - NC_052536.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The authors investigated the effect of a multiallelic indel in the CDKN3 gene on the economic traits of chickens, and this indel was significantly associated with growth and carcass traits in chickens. Collectively, the findings provide useful information about the repeat sequence indel in the promoter region of the CDKN3 gene as a potential molecular marker for chicken breeding.
Title: A multiallelic indel in the promoter region of the Cyclin-dependent kinase inhibitor 3 gene is significantly associated with body weight and carcass traits in chickens.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein tyrosine phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein tyrosine/serine/threonine phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein dephosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: cyclin-dependent kinase inhibitor 3

Names: cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase)

NP_001239091.2

EC 3.1.3.16

EC 3.1.3.48

XP_046797838.1

EC 3.1.3.16

EC 3.1.3.48

XP_046797839.1

EC 3.1.3.16

EC 3.1.3.48

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001252162.2 → NP_001239091.2 cyclin-dependent kinase inhibitor 3

Status: VALIDATED

Source sequence(s)

JAENSK010000215

UniProtKB/TrEMBL

A0A8V0Z9J1

Conserved Domains (1) summary

cd14505
Location:25 → 186

CDKN3-like; cyclin-dependent kinase inhibitor 3 and similar proteins

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

56070550..56077439 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046941883.1 → XP_046797839.1 cyclin-dependent kinase inhibitor 3 isoform X2
XM_046941882.1 → XP_046797838.1 cyclin-dependent kinase inhibitor 3 isoform X1

UniProtKB/TrEMBL

A0A8V0Z256

Related

ENSGALP00010027305.1, ENSGALT00010045815.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

56111847..56118714 complement

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GenBank, FASTA, Sequence Viewer (Graphics)