U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PTPN21 protein tyrosine phosphatase non-receptor type 21 [ Gallus gallus (chicken) ]

Gene ID: 423398, updated on 13-Apr-2026
Symbol
PTPN21provided by CGNC
Full Name
protein tyrosine phosphatase non-receptor type 21provided by CGNC
Primary source
CGNC:8060
See related
Ensembl:ENSGALG00010017937
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See PTPN21 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
21
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (42604076..42645977, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (42566646..42608527, complement)

Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene potassium two pore domain channel subfamily K member 10 Neighboring gene uncharacterized LOC121110925 Neighboring gene spermatogenesis associated 7 Neighboring gene zinc finger CCCH-type containing 14 Neighboring gene EMAP like 5 Neighboring gene uncharacterized LOC121110924

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
tyrosine-protein phosphatase non-receptor type 21
XP_015143216.1
XP_025007054.1
XP_040528884.1
XP_040528885.1
XP_040528886.1
XP_421308.4

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    42604076..42645977 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_421308.8 → XP_421308.4  tyrosine-protein phosphatase non-receptor type 21 isoform X2

    UniProtKB/TrEMBL
    E1C5H0
    Related
    ENSGALP00010025772.1, ENSGALT00010043362.1
    Conserved Domains (4) summary
    smart00295
    Location:24 → 222
    B41; Band 4.1 homologues
    cd13188
    Location:217 → 307
    FERM_C_PTPN14_PTPN21; FERM domain C-lobe of Protein tyrosine phosphatase non-receptor proteins 14 and 21 (PTPN14 and 21)
    cd17192
    Location:20 → 106
    FERM_F1_PTPN21; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in tyrosine-protein phosphatase non-receptor type 21 (PTPN21) and similar proteins
    cl28904
    Location:894 → 1180
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  2. XM_015287730.4 → XP_015143216.1  tyrosine-protein phosphatase non-receptor type 21 isoform X1

    UniProtKB/TrEMBL
    A0A1D5P6Q1
    Related
    ENSGALP00010025770.1, ENSGALT00010043358.1
    Conserved Domains (4) summary
    smart00295
    Location:24 → 222
    B41; Band 4.1 homologues
    cd13188
    Location:217 → 307
    FERM_C_PTPN14_PTPN21; FERM domain C-lobe of Protein tyrosine phosphatase non-receptor proteins 14 and 21 (PTPN14 and 21)
    cd17192
    Location:20 → 106
    FERM_F1_PTPN21; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in tyrosine-protein phosphatase non-receptor type 21 (PTPN21) and similar proteins
    cl28904
    Location:928 → 1214
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  3. XM_025151286.3 → XP_025007054.1  tyrosine-protein phosphatase non-receptor type 21 isoform X1

    UniProtKB/TrEMBL
    A0A1D5P6Q1
    Conserved Domains (4) summary
    smart00295
    Location:24 → 222
    B41; Band 4.1 homologues
    cd13188
    Location:217 → 307
    FERM_C_PTPN14_PTPN21; FERM domain C-lobe of Protein tyrosine phosphatase non-receptor proteins 14 and 21 (PTPN14 and 21)
    cd17192
    Location:20 → 106
    FERM_F1_PTPN21; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in tyrosine-protein phosphatase non-receptor type 21 (PTPN21) and similar proteins
    cl28904
    Location:928 → 1214
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    42566646..42608527 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040672952.2 → XP_040528886.1  tyrosine-protein phosphatase non-receptor type 21 isoform X2

    UniProtKB/TrEMBL
    E1C5H0
    Conserved Domains (4) summary
    smart00295
    Location:24 → 222
    B41; Band 4.1 homologues
    cd13188
    Location:217 → 307
    FERM_C_PTPN14_PTPN21; FERM domain C-lobe of Protein tyrosine phosphatase non-receptor proteins 14 and 21 (PTPN14 and 21)
    cd17192
    Location:20 → 106
    FERM_F1_PTPN21; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in tyrosine-protein phosphatase non-receptor type 21 (PTPN21) and similar proteins
    cl28904
    Location:894 → 1180
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  2. XM_040672950.2 → XP_040528884.1  tyrosine-protein phosphatase non-receptor type 21 isoform X1

    UniProtKB/TrEMBL
    A0A1D5P6Q1
    Conserved Domains (4) summary
    smart00295
    Location:24 → 222
    B41; Band 4.1 homologues
    cd13188
    Location:217 → 307
    FERM_C_PTPN14_PTPN21; FERM domain C-lobe of Protein tyrosine phosphatase non-receptor proteins 14 and 21 (PTPN14 and 21)
    cd17192
    Location:20 → 106
    FERM_F1_PTPN21; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in tyrosine-protein phosphatase non-receptor type 21 (PTPN21) and similar proteins
    cl28904
    Location:928 → 1214
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

  3. XM_040672951.2 → XP_040528885.1  tyrosine-protein phosphatase non-receptor type 21 isoform X1

    UniProtKB/TrEMBL
    A0A1D5P6Q1
    Conserved Domains (4) summary
    smart00295
    Location:24 → 222
    B41; Band 4.1 homologues
    cd13188
    Location:217 → 307
    FERM_C_PTPN14_PTPN21; FERM domain C-lobe of Protein tyrosine phosphatase non-receptor proteins 14 and 21 (PTPN14 and 21)
    cd17192
    Location:20 → 106
    FERM_F1_PTPN21; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in tyrosine-protein phosphatase non-receptor type 21 (PTPN21) and similar proteins
    cl28904
    Location:928 → 1214
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials