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Dl Delta [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42313, updated on 10-Oct-2019

Summary

Official Symbol
Dlprovided by FlyBase
Official Full Name
Deltaprovided by FlyBase
Primary source
FLYBASE:FBgn0000463
Locus tag
Dmel_CG3619
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
0495/20; 0926/11; 1053/14; 1119/09; 1304/03; 1423/11; 1440/11; 1485/04; anon-WO0118547.269; C1; CG3619; CT12133; D; delta; delta D1; dl; DL; dmDelta; Dmel\CG3619; E(ls)2; EC3-5; l(3)05151; l(3)92Ab; l(3)j8C3

Genomic context

Location:
92A1-92A2; 3-66 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.26 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (19302731..19326217, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (15128453..15151939, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43451 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44175 Neighboring gene hairpin RNA:CR46343 Neighboring gene long non-coding RNA:CR43258

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
Notch binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Notch binding IDA
Inferred from Direct Assay
more info
PubMed 
Notch binding IPI
Inferred from Physical Interaction
more info
PubMed 
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
glycosphingolipid binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
receptor ligand activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
Notch signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Notch signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
Notch signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
Notch signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
actin filament organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
antennal morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
apposition of dorsal and ventral imaginal disc-derived wing surfaces IMP
Inferred from Mutant Phenotype
more info
PubMed 
asymmetric cell division TAS
Traceable Author Statement
more info
PubMed 
border follicle cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell fate specification TAS
Traceable Author Statement
more info
PubMed 
chaeta morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
compound eye cone cell fate commitment TAS
Traceable Author Statement
more info
PubMed 
compound eye retinal cell programmed cell death TAS
Traceable Author Statement
more info
PubMed 
dorsal/ventral lineage restriction, imaginal disc TAS
Traceable Author Statement
more info
PubMed 
ectoderm development TAS
Traceable Author Statement
more info
PubMed 
establishment of ommatidial planar polarity TAS
Traceable Author Statement
more info
PubMed 
germ-line stem cell population maintenance IMP
Inferred from Mutant Phenotype
more info
PubMed 
glial cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
imaginal disc-derived leg morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
imaginal disc-derived leg segmentation IMP
Inferred from Mutant Phenotype
more info
PubMed 
imaginal disc-derived wing margin morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
imaginal disc-derived wing morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
lateral inhibition IMP
Inferred from Mutant Phenotype
more info
PubMed 
mesoderm development IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of Notch signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of neurogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
neuron fate specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
oocyte localization involved in germarium-derived egg chamber formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
oogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
ovarian follicle cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
ovarian follicle cell stalk formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
peripheral nervous system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of mitotic cell cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
second mitotic wave involved in compound eye morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
sensory organ development IMP
Inferred from Mutant Phenotype
more info
PubMed 
stem cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
wing disc anterior/posterior pattern formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
wing disc dorsal/ventral pattern formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
adherens junction IDA
Inferred from Direct Assay
more info
PubMed 
apical cortex IDA
Inferred from Direct Assay
more info
PubMed 
cell surface IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasmic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with cytoplasmic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
early endosome IDA
Inferred from Direct Assay
more info
PubMed 
endocytic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
endosome IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
subapical complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
delta
Names
CG3619-PA
CG3619-PB
CG3619-PC
Dl-PA
Dl-PB
Dl-PC
complementation group 1
overflow

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    19302731..19326217 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_057916.4NP_477264.1  delta, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_477264.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P10041
    UniProtKB/TrEMBL
    A4V346
    Related
    FBpp0083153, FBtr0083739
    Conserved Domains (3) summary
    cd00054
    Location:529564
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam01414
    Location:164226
    DSL; Delta serrate ligand
    pfam07657
    Location:2396
    MNNL; N terminus of Notch ligand
  2. NM_001260264.2NP_001247193.1  delta, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247193.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P10041
    UniProtKB/TrEMBL
    A4V346
    Related
    FBpp0293200, FBtr0304658
    Conserved Domains (3) summary
    cd00054
    Location:529564
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam01414
    Location:164226
    DSL; Delta serrate ligand
    pfam07657
    Location:2396
    MNNL; N terminus of Notch ligand
  3. NM_169853.3NP_732412.1  delta, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732412.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P10041
    UniProtKB/TrEMBL
    A4V346
    Related
    FBpp0083154, FBtr0083740
    Conserved Domains (3) summary
    cd00054
    Location:529564
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam01414
    Location:164226
    DSL; Delta serrate ligand
    pfam07657
    Location:2396
    MNNL; N terminus of Notch ligand
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