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RBPJ recombination signal binding protein for immunoglobulin kappa J region [ Gallus gallus (chicken) ]

Gene ID: 422802, updated on 3-Dec-2024

Summary

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Symbol
RBPJprovided by CGNC
Full Name
recombination signal binding protein for immunoglobulin kappa J regionprovided by CGNC
Primary source
CGNC:10692
See related
Ensembl:ENSGALG00010010837
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
RBPJk
Orthologs
human mouse all
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Genomic context

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See RBPJ in Genome Data Viewer
Location:
chromosome: 4
Exon count:
21
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (72747615..72891389, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (72729811..72874132, complement)

Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene TBC1 domain family member 19 Neighboring gene cholecystokinin A receptor Neighboring gene small integral membrane protein 20 Neighboring gene SEL1L family member 3 Neighboring gene solute carrier family 34 member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ptf1a/Rbpj complex inhibits ganglion cell fate and drives the specification of all horizontal cell subtypes in the chick retina. Lelièvre EC, et al. Dev Biol, 2011 Oct 15. PMID 21839069
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. the Rbpj-interacting domains of Ptf1a protein were required for its effects on retinal ganglion cell fate specification
    Title: Ptf1a/Rbpj complex inhibits ganglion cell fate and drives the specification of all horizontal cell subtypes in the chick retina.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of MAML1-RBP-Jkappa- ICN1 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
recombining binding protein suppressor of hairless

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    72747615..72891389 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046940616.1 → XP_046796572.1  recombining binding protein suppressor of hairless isoform X5

    UniProtKB/TrEMBL
    A0A8V0Y6Q4

  2. XM_420752.8 → XP_420752.2  recombining binding protein suppressor of hairless isoform X6

    UniProtKB/TrEMBL
    A0A3Q2UCS9, A0A8V0Y6L7
    Related
    ENSGALP00010014634.1, ENSGALT00010025973.1
    Conserved Domains (3) summary
    cd01176
    Location:334 → 430
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:190 → 312
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:32 → 157
    LAG1-DNAbind; LAG1, DNA binding

  3. XM_046940620.1 → XP_046796576.1  recombining binding protein suppressor of hairless isoform X8

    UniProtKB/TrEMBL
    A0A1D5PM75, A0A8V0Y6L7, F1NIJ8

  4. XM_046940618.1 → XP_046796574.1  recombining binding protein suppressor of hairless isoform X8

    UniProtKB/TrEMBL
    A0A1D5PM75, A0A8V0Y6L7, F1NIJ8
    Related
    ENSGALP00010014629.1, ENSGALT00010025968.1

  5. XM_046940621.1 → XP_046796577.1  recombining binding protein suppressor of hairless isoform X8

    UniProtKB/TrEMBL
    A0A1D5PM75, A0A8V0Y6L7, F1NIJ8

  6. XM_015285708.4 → XP_015141194.1  recombining binding protein suppressor of hairless isoform X4

    UniProtKB/TrEMBL
    A0A8V0Y6L7
    Related
    ENSGALP00010014593.1, ENSGALT00010025926.1
    Conserved Domains (3) summary
    cd01176
    Location:337 → 433
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:193 → 315
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:35 → 160
    LAG1-DNAbind; LAG1, DNA binding

  7. XM_046940615.1 → XP_046796571.1  recombining binding protein suppressor of hairless isoform X3

    UniProtKB/TrEMBL
    A0A8V0Y6L7, A0A8V0Y8A1
    Related
    ENSGALP00010014626.1, ENSGALT00010025965.1

  8. XM_046940617.1 → XP_046796573.1  recombining binding protein suppressor of hairless isoform X7

    UniProtKB/TrEMBL
    A0A8V0Y6L7, A0A8V0Y896
    Related
    ENSGALP00010014621.1, ENSGALT00010025957.1

  9. XM_046940619.1 → XP_046796575.1  recombining binding protein suppressor of hairless isoform X8

    UniProtKB/TrEMBL
    A0A1D5PM75, A0A8V0Y6L7, F1NIJ8

  10. XM_004936138.5 → XP_004936195.1  recombining binding protein suppressor of hairless isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y210, A0A8V0Y6L7
    Related
    ENSGALP00010014614.1, ENSGALT00010025950.1
    Conserved Domains (3) summary
    cd01176
    Location:348 → 444
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:204 → 326
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:46 → 171
    LAG1-DNAbind; LAG1, DNA binding

  11. XM_040699295.2 → XP_040555229.1  recombining binding protein suppressor of hairless isoform X8

    UniProtKB/TrEMBL
    A0A1D5PM75, A0A8V0Y6L7, F1NIJ8
    Conserved Domains (3) summary
    cd01176
    Location:315 → 411
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:171 → 293
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:13 → 138
    LAG1-DNAbind; LAG1, DNA binding

  12. XM_046940614.1 → XP_046796570.1  recombining binding protein suppressor of hairless isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y206, A0A8V0Y6L7
    Related
    ENSGALP00010014609.1, ENSGALT00010025945.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    72729811..72874132 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046916871.1 → XP_046772827.1  recombining binding protein suppressor of hairless isoform X5

    UniProtKB/TrEMBL
    A0A8V0Y6Q4

  2. XM_040670210.2 → XP_040526144.1  recombining binding protein suppressor of hairless isoform X6

    UniProtKB/TrEMBL
    A0A3Q2UCS9, A0A8V0Y6L7
    Conserved Domains (3) summary
    cd01176
    Location:334 → 430
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:190 → 312
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:32 → 157
    LAG1-DNAbind; LAG1, DNA binding

  3. XM_046916873.1 → XP_046772829.1  recombining binding protein suppressor of hairless isoform X8

    UniProtKB/TrEMBL
    A0A1D5PM75, A0A8V0Y6L7, F1NIJ8

  4. XM_046916875.1 → XP_046772831.1  recombining binding protein suppressor of hairless isoform X8

    UniProtKB/TrEMBL
    A0A1D5PM75, A0A8V0Y6L7, F1NIJ8

  5. XM_040670209.2 → XP_040526143.1  recombining binding protein suppressor of hairless isoform X4

    UniProtKB/TrEMBL
    A0A8V0Y6L7
    Conserved Domains (3) summary
    cd01176
    Location:337 → 433
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:193 → 315
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:35 → 160
    LAG1-DNAbind; LAG1, DNA binding

  6. XM_046916870.1 → XP_046772826.1  recombining binding protein suppressor of hairless isoform X3

    UniProtKB/TrEMBL
    A0A8V0Y6L7, A0A8V0Y8A1

  7. XM_046916872.1 → XP_046772828.1  recombining binding protein suppressor of hairless isoform X7

    UniProtKB/TrEMBL
    A0A8V0Y6L7, A0A8V0Y896

  8. XM_046916874.1 → XP_046772830.1  recombining binding protein suppressor of hairless isoform X8

    UniProtKB/TrEMBL
    A0A1D5PM75, A0A8V0Y6L7, F1NIJ8

  9. XM_040670211.2 → XP_040526145.1  recombining binding protein suppressor of hairless isoform X8

    UniProtKB/TrEMBL
    A0A1D5PM75, A0A8V0Y6L7, F1NIJ8
    Conserved Domains (3) summary
    cd01176
    Location:315 → 411
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:171 → 293
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:13 → 138
    LAG1-DNAbind; LAG1, DNA binding

  10. XM_040670208.2 → XP_040526142.1  recombining binding protein suppressor of hairless isoform X9

    UniProtKB/TrEMBL
    A0A8V0Y6L7
    Conserved Domains (1) summary
    cd01176
    Location:339 → 435
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...

  11. XM_040670207.2 → XP_040526141.1  recombining binding protein suppressor of hairless isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y210, A0A8V0Y6L7
    Conserved Domains (3) summary
    cd01176
    Location:348 → 444
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:204 → 326
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:46 → 171
    LAG1-DNAbind; LAG1, DNA binding

  12. XM_040670212.2 → XP_040526146.1  recombining binding protein suppressor of hairless isoform X8

    UniProtKB/TrEMBL
    A0A1D5PM75, A0A8V0Y6L7, F1NIJ8
    Conserved Domains (3) summary
    cd01176
    Location:315 → 411
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:171 → 293
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:13 → 138
    LAG1-DNAbind; LAG1, DNA binding

  13. XM_046916869.1 → XP_046772825.1  recombining binding protein suppressor of hairless isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y6L7
Nucleotide Protein Strain
Heading Accession and Version

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