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FBXW7 F-box and WD repeat domain containing 7 [ Gallus gallus (chicken) ]

Gene ID: 422481, updated on 5-Mar-2024

Summary

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Symbol
FBXW7provided by CGNC
Full Name
F-box and WD repeat domain containing 7provided by CGNC
Primary source
CGNC:7676
See related
Ensembl:ENSGALG00010007590
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
17
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (33255033..33420934, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (33207481..33373153, complement)

Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107051776 Neighboring gene glutamyl-tRNA amidotransferase subunit B Neighboring gene uncharacterized LOC107051777 Neighboring gene uncharacterized LOC107051775 Neighboring gene translation initiation factor IF-2-like Neighboring gene uncharacterized LOC107051774 Neighboring gene transmembrane protein 154 Neighboring gene ADP ribosylation factor interacting protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expressed sequence tags for the chicken genome from a normalized 10-day-old White Leghorn whole embryo cDNA library: 1. DNA sequence characterization and linkage analysis. Smith EJ, et al. J Hered, 2001 Jan-Feb. PMID 11336223
  2. Chicken genomics resource: sequencing and annotation of 35,407 ESTs from single and multiple tissue cDNA libraries and CAP3 assembly of a chicken gene index. Carre W, et al. Physiol Genomics, 2006 May 16. PMID 16554550
  3. A comprehensive collection of chicken cDNAs. Boardman PE, et al. Curr Biol, 2002 Nov 19. PMID 12445392

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ubiquitin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ubiquitin recycling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
F-box/WD repeat-containing protein 7
Names
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001349722.3 → NP_001336651.1  F-box/WD repeat-containing protein 7

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) has twelve exons.
    Source sequence(s)
    AW328786, BU130459, BU371236, BU461175, CD214829, CD216216, HAEK01029958, JAENSK010000073
    Conserved Domains (3) summary
    cd00200
    Location:369 → 645
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:379 → 414
    7WD40; WD40 repeat [structural motif]
    pfam12937
    Location:276 → 320
    F-box-like

  2. NM_001397789.1 → NP_001384718.1  F-box/WD repeat-containing protein 7

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has eleven exons.
    Source sequence(s)
    AW328786, BU130459, BU371236, BU461175, CD214829, CD216216, HAEK01029958, JAENSK010000073
    UniProtKB/TrEMBL
    A0A1D5PCK8
    Related
    ENSGALP00010009956.1, ENSGALT00010018074.1
    Conserved Domains (3) summary
    smart00256
    Location:163 → 203
    FBOX; A Receptor for Ubiquitination Targets
    cd00200
    Location:253 → 529
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:263 → 298
    7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    33255033..33420934 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040698905.2 → XP_040554839.1  F-box/WD repeat-containing protein 7 isoform X1

    Conserved Domains (3) summary
    cd00200
    Location:369 → 645
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:379 → 414
    7WD40; WD40 repeat [structural motif]
    pfam12937
    Location:276 → 320
    F-box-like

  2. XM_040698906.2 → XP_040554840.1  F-box/WD repeat-containing protein 7 isoform X2

    Conserved Domains (3) summary
    cd00200
    Location:256 → 532
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:266 → 301
    7WD40; WD40 repeat [structural motif]
    pfam12937
    Location:163 → 207
    F-box-like

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    33207481..33373153 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046915933.1 → XP_046771889.1  F-box/WD repeat-containing protein 7 isoform X3

  2. XM_046915934.1 → XP_046771890.1  F-box/WD repeat-containing protein 7 isoform X2

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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