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14-3-3epsilon [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42186, updated on 12-Aug-2018

Summary

Official Symbol
14-3-3epsilonprovided by FlyBase
Primary source
FLYBASE:FBgn0020238
Locus tag
Dmel_CG31196
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
14-3-3; 14-3-3 epsilon; 14-3-3-e; 14-3-3-epsilon; 14-3-30epsilon; 14-3-3e; 14-3-3EPSILON; 14-3-3omicron; 14.3.3 epsilon; 1433epsilon; 143E_DROME; anon-WO0172774.141; anon-WO02059370.52; CG31196; CT24092; D14-3-3e; d14-3-3epsilon; D14-3-3epsilon; Dmel\CG31196; e-14-3-3; EK3-5; eps; l(3)j2B10; par-5; Par-5; PAR-5; PAR5; SR3-9; Su(Raf)3B

Genomic context

See 14-3-3epsilon in Genome Data Viewer
Location:
90F10-90F10; 3-62 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18242531..18250550)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14068253..14076272)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Malate dehydrogenase 2 Neighboring gene reversed polarity Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene transcriptional Adaptor 2a Neighboring gene RNA polymerase II subunit Rpb4

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
phosphoserine residue binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein domain specific binding IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
transcription factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
DNA damage checkpoint IMP
Inferred from Mutant Phenotype
more info
PubMed 
DNA damage checkpoint TAS
Traceable Author Statement
more info
PubMed 
axon guidance IMP
Inferred from Mutant Phenotype
more info
PubMed 
cytoplasmic sequestering of transcription factor IMP
Inferred from Mutant Phenotype
more info
PubMed 
determination of adult lifespan IMP
Inferred from Mutant Phenotype
more info
PubMed 
germarium-derived oocyte fate determination IMP
Inferred from Mutant Phenotype
more info
PubMed 
imaginal disc development TAS
Traceable Author Statement
more info
PubMed 
mitotic cell cycle checkpoint TAS
Traceable Author Statement
more info
PubMed 
oocyte microtubule cytoskeleton polarization IMP
Inferred from Mutant Phenotype
more info
PubMed 
pole cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of Ras protein signal transduction HGI PubMed 
positive regulation of growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of hippo signaling IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of growth IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of mitotic nuclear division IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to UV IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to radiation TAS
Traceable Author Statement
more info
PubMed 
wing disc dorsal/ventral pattern formation IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
centrosome HDA PubMed 
chromosome IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm HDA PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
germline ring canal IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm HDA PubMed 
nucleus HDA PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane HDA PubMed 

General protein information

Preferred Names
14-3-3epsilon
Names
14-3-3 epsilon
14-3-3 protein epsilon
14-3-3&epsilon
14-3-3epsilon-PA
14-3-3epsilon-PB
14-3-3epsilon-PC
14-3-3epsilon-PD
CG31196-PA
CG31196-PB
CG31196-PC
CG31196-PD
Tyrosine-3-monooxygenase
epsilon
suppressor of Ras85D 3-9

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    18242531..18250550
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_169798.3NP_732311.1  14-3-3epsilon, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732311.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P92177
    Related
    FBpp0082990.1, FBtr0083568
    Conserved Domains (1) summary
    cd10020
    Location:4233
    14-3-3_epsilon; 14-3-3 epsilon, an isoform of 14-3-3 protein
  2. NM_169797.3NP_732310.1  14-3-3epsilon, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732310.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P92177
    Related
    FBpp0082988.1, FBtr0083566
    Conserved Domains (1) summary
    cd10020
    Location:4233
    14-3-3_epsilon; 14-3-3 epsilon, an isoform of 14-3-3 protein
  3. NM_169796.2NP_732309.1  14-3-3epsilon, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732309.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P92177
    UniProtKB/TrEMBL
    C6TP70
    Related
    FBpp0082987.1, FBtr0083565
    Conserved Domains (1) summary
    cd10020
    Location:4233
    14-3-3_epsilon; 14-3-3 epsilon, an isoform of 14-3-3 protein
  4. NM_169799.2NP_732312.1  14-3-3epsilon, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732312.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P92177
    Related
    FBpp0082989.1, FBtr0083567
    Conserved Domains (1) summary
    cd10020
    Location:4233
    14-3-3_epsilon; 14-3-3 epsilon, an isoform of 14-3-3 protein
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