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IARS2 isoleucyl-tRNA synthetase 2, mitochondrial [ Gallus gallus (chicken) ]

Gene ID: 421346, updated on 26-Mar-2025
Symbol
IARS2provided by CGNC
Full Name
isoleucyl-tRNA synthetase 2, mitochondrialprovided by CGNC
Primary source
CGNC:7282
See related
Ensembl:ENSGALG00010016087
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
ileRS
Orthologs
human mouse all
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See IARS2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
23
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (18478384..18503051, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (18391927..18416553, complement)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110454 Neighboring gene RAB3 GTPase activating non-catalytic protein subunit 2 Neighboring gene uncharacterized LOC121113144 Neighboring gene microRNA 194-1 Neighboring gene microRNA 215 Neighboring gene 3'(2'), 5'-bisphosphate nucleotidase 1 Neighboring gene glutamyl-prolyl-tRNA synthetase

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables aminoacyl-tRNA deacylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables isoleucine-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tRNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in isoleucyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
isoleucine--tRNA ligase, mitochondrial
Names
isoleucine-tRNA synthetase 2, mitochondrial
isoleucyl-tRNA synthetase, mitochondrial
NP_001006397.1
XP_040552980.1
XP_046769669.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001006397.2 → NP_001006397.1  isoleucine--tRNA ligase, mitochondrial precursor

    See identical proteins and their annotated locations for NP_001006397.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000062
    UniProtKB/Swiss-Prot
    Q5ZKA2
    Related
    ENSGALP00010022380.1, ENSGALT00010038696.1
    Conserved Domains (4) summary
    cd07960
    Location:696 → 875
    Anticodon_Ia_Ile_BEm; Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases
    PRK05743
    Location:44 → 996
    ileS; isoleucyl-tRNA synthetase; Reviewed
    pfam13603
    Location:340 → 396
    tRNA-synt_1_2; Leucyl-tRNA synthetase, Domain 2
    cl00015
    Location:457 → 693
    nt_trans; nucleotidyl transferase superfamily

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    18478384..18503051 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040697046.1 → XP_040552980.1  isoleucine--tRNA ligase, mitochondrial isoform X1

    Conserved Domains (1) summary
    PRK05743
    Location:2 → 870
    ileS; isoleucyl-tRNA synthetase; Reviewed

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    18391927..18416553 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046913713.1 → XP_046769669.1  isoleucine--tRNA ligase, mitochondrial isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5ZKA2.1 GenPept UniProtKB/Swiss-Prot:Q5ZKA2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials