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RBBP8 RB binding protein 8, endonuclease [ Gallus gallus (chicken) ]

Gene ID: 421071, updated on 13-Apr-2026
Symbol
RBBP8provided by CGNC
Full Name
RB binding protein 8, endonucleaseprovided by CGNC
Primary source
CGNC:11132
See related
Ensembl:ENSGALG00010004142
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
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Try the new Transcripts and proteins table
See RBBP8 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
23
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (102440119..102478333)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (102504600..102543087)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene GATA binding protein 6 Neighboring gene uncharacterized LOC101751137 Neighboring gene uncharacterized LOC107052000 Neighboring gene Cdk5 and Abl enzyme substrate 1 Neighboring gene transmembrane protein 241 Neighboring gene RIO kinase 3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Collaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repair. Nakamura K, et al. PLoS Genet, 2010 Jan 22. PMID 20107609, Free PMC Article
  2. CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle. Yun MH, et al. Nature, 2009 May 21. PMID 19357644, Free PMC Article
  3. FANCD2 binds CtIP and regulates DNA-end resection during DNA interstrand crosslink repair. Unno J, et al. Cell Rep, 2014 May 22. PMID 24794430
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. BRCA1-CtIP complex plays a role in the nuclease-mediated elimination of oligonucleotides covalently bound to polypeptides from double-strand breaks, thereby facilitating DNA repair.
    Title: Collaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repair.
  2. CtIP is required not only for repair of double strand breaks by homologous recombination in S/G2 phase but also for microhomology-mediated end-joining in G1
    Title: CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Y-form DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables damaged DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-strand/single-strand DNA junction binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables flap-structured DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA double-strand break processing involved in repair via single-strand annealing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in site of double-strand break IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
DNA endonuclease RBBP8
Names
retinoblastoma binding protein 8

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    102440119..102478333
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015277972.4 → XP_015133458.2  DNA endonuclease RBBP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XLL3
    Conserved Domains (1) summary
    TIGR02169
    Location:22 → 147
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  2. XM_046938209.1 → XP_046794165.1  DNA endonuclease RBBP8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XG43, A0A8V0XLL3

  3. XM_015277973.4 → XP_015133459.2  DNA endonuclease RBBP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XLL3
    Conserved Domains (1) summary
    TIGR02169
    Location:22 → 147
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  4. XM_040688348.2 → XP_040544282.1  DNA endonuclease RBBP8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XG43, A0A8V0XLL3
    Conserved Domains (1) summary
    COG1196
    Location:22 → 184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  5. XM_040688366.2 → XP_040544300.1  DNA endonuclease RBBP8 isoform X4

    UniProtKB/TrEMBL
    A0A8V0XLL3
    Conserved Domains (1) summary
    COG1196
    Location:22 → 184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  6. XM_015277968.4 → XP_015133454.2  DNA endonuclease RBBP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XLL3
    Conserved Domains (1) summary
    TIGR02169
    Location:22 → 147
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  7. XM_040688308.2 → XP_040544242.1  DNA endonuclease RBBP8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XG43, A0A8V0XLL3
    Conserved Domains (1) summary
    COG1196
    Location:22 → 184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  8. XM_046938212.1 → XP_046794168.1  DNA endonuclease RBBP8 isoform X4

    UniProtKB/TrEMBL
    A0A8V0XLL3

  9. XM_046938207.1 → XP_046794163.1  DNA endonuclease RBBP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XLL3

  10. XM_040688339.2 → XP_040544273.1  DNA endonuclease RBBP8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XG43, A0A8V0XLL3
    Conserved Domains (1) summary
    COG1196
    Location:22 → 184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  11. XM_015277971.4 → XP_015133457.2  DNA endonuclease RBBP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XLL3
    Conserved Domains (1) summary
    TIGR02169
    Location:22 → 147
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  12. XM_046938208.1 → XP_046794164.1  DNA endonuclease RBBP8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XG43, A0A8V0XLL3

  13. XM_015277970.4 → XP_015133456.2  DNA endonuclease RBBP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XLL3
    Conserved Domains (1) summary
    TIGR02169
    Location:22 → 147
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  14. XM_040688329.2 → XP_040544263.1  DNA endonuclease RBBP8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XG43, A0A8V0XLL3
    Related
    ENSGALP00010005678.1, ENSGALT00010009669.1
    Conserved Domains (1) summary
    COG1196
    Location:22 → 184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  15. XM_015277969.4 → XP_015133455.2  DNA endonuclease RBBP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XLL3
    Conserved Domains (1) summary
    TIGR02169
    Location:22 → 147
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  16. XM_025147893.3 → XP_025003661.2  DNA endonuclease RBBP8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XG43, A0A8V0XLL3
    Related
    ENSGALP00010005674.1, ENSGALT00010009665.1
    Conserved Domains (1) summary
    COG1196
    Location:22 → 184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  17. XM_046938211.1 → XP_046794167.1  DNA endonuclease RBBP8 isoform X4

    UniProtKB/TrEMBL
    A0A8V0XLL3

  18. XM_004939771.5 → XP_004939828.2  DNA endonuclease RBBP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XLL3
    Conserved Domains (1) summary
    TIGR02169
    Location:22 → 147
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  19. XM_046938210.1 → XP_046794166.1  DNA endonuclease RBBP8 isoform X3

    UniProtKB/TrEMBL
    A0A8V0XLL3

  20. XM_419158.7 → XP_419158.2  DNA endonuclease RBBP8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XG43, A0A8V0XLL3
    Conserved Domains (1) summary
    COG1196
    Location:22 → 184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  21. XM_046938213.1 → XP_046794169.1  DNA endonuclease RBBP8 isoform X4

    UniProtKB/TrEMBL
    A0A8V0XLL3

  22. XM_040688298.1 → XP_040544232.1  DNA endonuclease RBBP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XLL3
    Conserved Domains (1) summary
    TIGR02169
    Location:22 → 147
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  23. XM_046938214.1 → XP_046794170.1  DNA endonuclease RBBP8 isoform X5

    UniProtKB/TrEMBL
    A0A8V0XLL3

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    102504600..102543087
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040665581.2 → XP_040521515.1  DNA endonuclease RBBP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XLL3
    Conserved Domains (1) summary
    TIGR02169
    Location:22 → 147
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  2. XM_046912705.1 → XP_046768661.1  DNA endonuclease RBBP8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XG43, A0A8V0XLL3

  3. XM_040665578.2 → XP_040521512.1  DNA endonuclease RBBP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XLL3
    Conserved Domains (1) summary
    TIGR02169
    Location:22 → 147
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  4. XM_040665587.2 → XP_040521521.1  DNA endonuclease RBBP8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XG43, A0A8V0XLL3
    Conserved Domains (1) summary
    COG1196
    Location:22 → 184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  5. XM_040665590.2 → XP_040521524.1  DNA endonuclease RBBP8 isoform X4

    UniProtKB/TrEMBL
    A0A8V0XLL3
    Conserved Domains (1) summary
    COG1196
    Location:22 → 184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  6. XM_040665577.2 → XP_040521511.1  DNA endonuclease RBBP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XLL3
    Conserved Domains (1) summary
    TIGR02169
    Location:22 → 147
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  7. XM_040665583.2 → XP_040521517.1  DNA endonuclease RBBP8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XG43, A0A8V0XLL3
    Conserved Domains (1) summary
    COG1196
    Location:22 → 184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  8. XM_046912708.1 → XP_046768664.1  DNA endonuclease RBBP8 isoform X4

    UniProtKB/TrEMBL
    A0A8V0XLL3

  9. XM_046912703.1 → XP_046768659.1  DNA endonuclease RBBP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XLL3

  10. XM_040665586.2 → XP_040521520.1  DNA endonuclease RBBP8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XG43, A0A8V0XLL3
    Conserved Domains (1) summary
    COG1196
    Location:22 → 184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  11. XM_040665579.2 → XP_040521513.1  DNA endonuclease RBBP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XLL3
    Conserved Domains (1) summary
    TIGR02169
    Location:22 → 147
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  12. XM_046912704.1 → XP_046768660.1  DNA endonuclease RBBP8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XG43, A0A8V0XLL3

  13. XM_040665580.2 → XP_040521514.1  DNA endonuclease RBBP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XLL3
    Conserved Domains (1) summary
    TIGR02169
    Location:22 → 147
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  14. XM_040665585.2 → XP_040521519.1  DNA endonuclease RBBP8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XG43, A0A8V0XLL3
    Conserved Domains (1) summary
    COG1196
    Location:22 → 184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  15. XM_040665575.2 → XP_040521509.1  DNA endonuclease RBBP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XLL3
    Conserved Domains (1) summary
    TIGR02169
    Location:22 → 147
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  16. XM_040665584.2 → XP_040521518.1  DNA endonuclease RBBP8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XG43, A0A8V0XLL3
    Conserved Domains (1) summary
    COG1196
    Location:22 → 184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  17. XM_046912707.1 → XP_046768663.1  DNA endonuclease RBBP8 isoform X4

    UniProtKB/TrEMBL
    A0A8V0XLL3

  18. XM_040665576.2 → XP_040521510.1  DNA endonuclease RBBP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XLL3
    Conserved Domains (1) summary
    TIGR02169
    Location:22 → 147
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  19. XM_046912706.1 → XP_046768662.1  DNA endonuclease RBBP8 isoform X3

    UniProtKB/TrEMBL
    A0A8V0XLL3

  20. XM_040665588.2 → XP_040521522.1  DNA endonuclease RBBP8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XG43, A0A8V0XLL3
    Conserved Domains (1) summary
    COG1196
    Location:22 → 184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  21. XM_046912709.1 → XP_046768665.1  DNA endonuclease RBBP8 isoform X4

    UniProtKB/TrEMBL
    A0A8V0XLL3

  22. XM_040665582.1 → XP_040521516.1  DNA endonuclease RBBP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XLL3
    Conserved Domains (1) summary
    TIGR02169
    Location:22 → 147
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  23. XM_046912711.1 → XP_046768667.1  DNA endonuclease RBBP8 isoform X5

    UniProtKB/TrEMBL
    A0A8V0XLL3
Nucleotide Protein Strain
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