MYLIP myosin regulatory light chain interacting protein [Gallus gallus (chicken)] - Gene

Summary

Symbol: MYLIPprovided by CGNC
Full Name: myosin regulatory light chain interacting proteinprovided by CGNC
Primary source: CGNC:9639
See related: Ensembl:ENSGALG00010011064
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: all
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Genomic context

Location:: chromosome: 2

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	2	NC_052533.1 (61209868..61224100)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	2	NC_052574.1 (61160245..61174477)

Chromosome 2 - NC_052533.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cytoskeletal protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ubiquitin-protein transferase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in ubiquitin-dependent protein catabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: E3 ubiquitin-protein ligase MYLIP

NP_001012579.1

EC 6.3.2.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001012561.2 → NP_001012579.1 E3 ubiquitin-protein ligase MYLIP

See identical proteins and their annotated locations for NP_001012579.1

Status: PROVISIONAL

Source sequence(s)

JAENSK010000040

UniProtKB/TrEMBL

A0A8V0YGF4, F1NWY9, Q5F429

Related

ENSGALP00010015081.1, ENSGALT00010026488.1

Conserved Domains (5) summary

smart00295
Location:5 → 190

B41; Band 4.1 homologues

cd13195
Location:185 → 295

FERM_C_MYLIP_IDOL; FERM domain C-lobe of E3 ubiquitin ligase myosin regulatory light chain-interacting protein (MYLIP; also called inducible degrader of the LDL receptor, IDOL)

pfam00373
Location:85 → 190

FERM_M; FERM central domain

pfam09379
Location:5 → 67

FERM_N; FERM N-terminal domain

pfam13920
Location:383 → 428

zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)