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CG5292 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42079, updated on 4-Apr-2024

Summary

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Official Symbol
CG5292provided by FlyBase
Primary source
FLYBASE:FBgn0038491
Locus tag
Dmel_CG5292
See related
AllianceGenome:FB:FBgn0038491
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RE41712; Dmel\CG5292
Summary
Predicted to enable tRNA-specific adenosine-34 deaminase activity. Predicted to be involved in tRNA wobble adenosine to inosine editing. Is expressed in several structures, including embryonic/larval midgut primordium; embryonic/larval salivary gland; and germline cell. Orthologous to human ADAT2 (adenosine deaminase tRNA specific 2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
89F1-89F1; 3-60 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (17151861..17153771)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (12977583..12979493)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Mucin related 89F Neighboring gene Single-strand-selective monofunctional uracil-DNA glycosylase Neighboring gene Deterin Neighboring gene uncharacterized protein Neighboring gene beaten path IIb Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. RNA editing by base deamination: more enzymes, more targets, new mysteries. Gerber AP, et al. Trends Biochem Sci, 2001 Jun. PMID 11406411
  2. Regulating gene expression in the Drosophila germ line. Rangan P, et al. Cold Spring Harb Symp Quant Biol, 2008. PMID 19270081
  3. Temporal and spatial control of germ-plasm RNAs. Rangan P, et al. Curr Biol, 2009 Jan 13. PMID 19110432, Free PMC Article
  4. Analysis of RNA Interference Lines Identifies New Functions of Maternally-Expressed Genes Involved in Embryonic Patterning in Drosophila melanogaster. Liu N, et al. G3 (Bethesda), 2015 Mar 31. PMID 25834215, Free PMC Article
  5. Proteomic Analysis of the Ubiquitin Landscape in the Drosophila Embryonic Nervous System and the Adult Photoreceptor Cells. Ramirez J, et al. PLoS One, 2015. PMID 26460970, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables tRNA-specific adenosine-34 deaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in tRNA wobble adenosine to inosine editing IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG5292-PA
CG5292-PB
NP_001262661.1
NP_650610.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    17151861..17153771
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275732.1 → NP_001262661.1  uncharacterized protein Dmel_CG5292, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262661.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VEM0
    Conserved Domains (1) summary
    COG0590
    Location:4 → 146
    TadA; tRNA(Arg) A34 adenosine deaminase TadA [Translation, ribosomal structure and biogenesis]

  2. NM_142353.3 → NP_650610.1  uncharacterized protein Dmel_CG5292, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650610.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VEM0
    Related
    FBpp0082851
    Conserved Domains (1) summary
    COG0590
    Location:4 → 146
    TadA; tRNA(Arg) A34 adenosine deaminase TadA [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VEM0 Q9VEM0

Gene LinkOut

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