VIM vimentin [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: VIMprovided by CGNC
Official Full Name: vimentinprovided by CGNC
Primary source: CGNC:51275
See related: Ensembl:ENSGALG00010004281
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	2	NC_052533.1 (19703300..19711012, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	2	NC_052574.1 (19733030..19740746, complement)

Chromosome 2 - NC_052533.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

3D-reconstructed images clearly revealed that high levels of taste receptor type 2 member 7 and T1R1 were expressed in Vimentin-negative taste bud cells.
Title: Bitter taste receptor T2R7 and umami taste receptor subunit T1R1 are expressed highly in Vimentin-negative taste bud cells in chickens.
These findings suggest a novel role for extracellular, cell-surface-associated vimentin in mediating repair-cell function in wound repair and in transitioning these cells to a myofibroblast phenotype.
Title: In wound repair vimentin mediates the transition of mesenchymal leader cells to a myofibroblast phenotype.
The dats of this study support the possible role of vimentin+ fibers in the structural events of cerebellum corticogenesis, suggesting the participation of radial/Bergmann glia in chicken cerebellum foliation.
Title: Transient vimentin expression during the embryonic development of the chicken cerebellum.
p17 suppresses both CDK1 and Plk1functions, disrupts vimentin phosphorylation, causes G2/M cell cycle arrest and thus benefits virus replication.
Title: Suppression of Vimentin Phosphorylation by the Avian Reovirus p17 through Inhibition of CDK1 and Plk1 Impacting the G2/M Phase of the Cell Cycle.
analysis of alpha-Gustducin and Vimentin distribution in premature and mature taste buds in chickens
Title: Distribution of α-Gustducin and Vimentin in premature and mature taste buds in chickens.
Vimentin has a central role in regulating repair function during healing of the lens epithelium.
Title: A central role for vimentin in regulating repair function during healing of the lens epithelium.
Data show O-GlcNAc modification of radial glial vimentin filaments in the developing chick brain.
Title: O-GlcNAc modification of radial glial vimentin filaments in the developing chick brain.
These findings document that up-regulation of vimentin gene expression is important for formation of fully active macrophage-like cells and macrophage polykaryons
Title: Role of vimentin in regulation of monocyte/macrophage differentiation.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

VIMsts1 (e-PCR), detects polymorphism
- UniSTS:280370

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables structural constituent of cytoskeleton	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in intermediate filament organization	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in axon	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in intermediate filament	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: vimentin

Names: vimentin C-terminus

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001048076.3 → NP_001041541.2 vimentin

Status: VALIDATED

Source sequence(s)

JAENSK010000036

UniProtKB/Swiss-Prot

P09654, Q91023

Related

ENSGALP00010005851.1, ENSGALT00010010008.1

Conserved Domains (3) summary

pfam00038
Location:96 → 404

Filament; Intermediate filament protein

pfam04732
Location:9 → 95

Filament_head; Intermediate filament head (DNA binding) region

cl24005
Location:284 → 362

DUF2570; Protein of unknown function (DUF2570)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

19703300..19711012 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

19733030..19740746 complement

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GenBank, FASTA, Sequence Viewer (Graphics)