U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

EMC2 ER membrane protein complex subunit 2 [ Gallus gallus (chicken) ]

Gene ID: 420273, updated on 5-Sep-2025
Symbol
EMC2provided by CGNC
Full Name
ER membrane protein complex subunit 2provided by CGNC
Primary source
CGNC:12029
See related
Ensembl:ENSGALG00010007952
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
TTC35
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table
See EMC2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
11
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (131293192..131328116)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (131500048..131534945)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 3 subunit E Neighboring gene uncharacterized LOC121109763 Neighboring gene uncharacterized LOC112531895 Neighboring gene transmembrane protein 74

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. ESTs from brain and testis of White Leghorn and red junglefowl: annotation, bioinformatic classification of unknown transcripts and analysis of expression levels. Savolainen P, et al. Cytogenet Genome Res, 2005. PMID 16093725
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein folding in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of EMC complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
ER membrane protein complex subunit 2
Names
tetratricopeptide repeat domain 35
tetratricopeptide repeat protein 35

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001198680.2 → NP_001185609.1  ER membrane protein complex subunit 2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000044
    UniProtKB/TrEMBL
    A0A3Q2UDL9, A0A8V0XZL4
    Related
    ENSGALP00010010513.1, ENSGALT00010018964.1
    Conserved Domains (3) summary
    sd00006
    Location:120 → 150
    TPR; TPR repeat [structural motif]
    pfam13414
    Location:156 → 222
    TPR_11; TPR repeat
    pfam14559
    Location:99 → 164
    TPR_19; Tetratricopeptide repeat

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    131293192..131328116
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040678627.2 → XP_040534561.1  ER membrane protein complex subunit 2 isoform X1

    UniProtKB/TrEMBL
    A0A1D5NVZ7, A0A8V0XZL4
    Related
    ENSGALP00010010510.1, ENSGALT00010018961.1
    Conserved Domains (2) summary
    TIGR02917
    Location:98 → 236
    PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
    sd00006
    Location:116 → 146
    TPR; TPR repeat [structural motif]

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    131500048..131534945
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials