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PIAS4 protein inhibitor of activated STAT 4 [ Gallus gallus (chicken) ]

Gene ID: 420095, updated on 13-Apr-2026
Symbol
PIAS4provided by CGNC
Full Name
protein inhibitor of activated STAT 4provided by CGNC
Primary source
CGNC:1292
See related
Ensembl:ENSGALG00010027113
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
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See PIAS4 in Genome Data Viewer
Location:
chromosome: 28
Exon count:
12
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 28 NC_052559.1 (1862147..1876376, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 28 NC_052600.1 (1428486..1442719, complement)

Chromosome 28 - NC_052559.1Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 7A Neighboring gene forkhead box protein L2-like Neighboring gene eukaryotic translation elongation factor 2 Neighboring gene Small nucleolar RNA SNORD37 Neighboring gene death-associated protein kinase 3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SUMO ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coregulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein sumoylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
E3 SUMO-protein ligase PIAS4
XP_015155317.1
XP_040509577.1
XP_040509578.1
XP_040548532.1
XP_040548533.1
XP_040548534.1

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052559.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    1862147..1876376 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015299831.4 → XP_015155317.1  E3 SUMO-protein ligase PIAS4 isoform X1

    UniProtKB/TrEMBL
    A0A1D5P2D1
    Related
    ENSGALP00010039984.1, ENSGALT00010065718.1
    Conserved Domains (3) summary
    smart00513
    Location:12 → 46
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:324 → 371
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:133 → 277
    PINIT; PINIT domain

  2. XM_040653643.2 → XP_040509577.1  E3 SUMO-protein ligase PIAS4 isoform X2

    Conserved Domains (2) summary
    smart00513
    Location:2 → 36
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:314 → 361
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins

  3. XM_040653644.2 → XP_040509578.1  E3 SUMO-protein ligase PIAS4 isoform X3

    Conserved Domains (2) summary
    smart00513
    Location:12 → 46
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:324 → 371
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052600.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    1428486..1442719 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040692598.2 → XP_040548532.1  E3 SUMO-protein ligase PIAS4 isoform X1

    UniProtKB/TrEMBL
    A0A1D5P2D1
    Conserved Domains (3) summary
    smart00513
    Location:12 → 46
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:324 → 371
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
    pfam14324
    Location:133 → 277
    PINIT; PINIT domain

  2. XM_040692599.2 → XP_040548533.1  E3 SUMO-protein ligase PIAS4 isoform X2

    Conserved Domains (2) summary
    smart00513
    Location:2 → 36
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:314 → 361
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins

  3. XM_040692600.2 → XP_040548534.1  E3 SUMO-protein ligase PIAS4 isoform X3

    Conserved Domains (2) summary
    smart00513
    Location:12 → 46
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd16790
    Location:324 → 371
    SP-RING_PIAS; SP-RING finger found in protein inhibitor of activated signal transducer and activator of transcription (PIAS) proteins
Nucleotide Protein Strain
Heading Accession and Version

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