LASP1 LIM and SH3 protein 1 [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: LASP1provided by CGNC
Official Full Name: LIM and SH3 protein 1provided by CGNC
Primary source: CGNC:1150
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: all
: Try the new Gene page
Try the new Transcripts and proteins table

Genomic context

Location:: chromosome: 27

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	27	NC_052558.1 (4037109..4057077)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	27	NC_052599.1 (5199623..5219613)

Chromosome 27 - NC_052558.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

chromosomal locations of the LASP1 and LASP2 genes; The LASP1 gene was localized to a pair of microchromosomes and the LASP2 gene was localized to chromosome 2p3.1
Title: Chromosomal assignment of LASP1 and LASP2 genes and organization of the LASP2 gene in chicken.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables actin filament binding	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in focal adhesion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: LIM and SH3 domain protein 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001177329.3 → NP_001170800.3 LIM and SH3 domain protein 1

Status: VALIDATED

Source sequence(s)

JAENSK010000365

UniProtKB/TrEMBL

A0A1D5PB50, D2Z1L9

Conserved Domains (4) summary

smart00227
Location:98 → 128

NEBU; The Nebulin repeat is present also in Las1

cd09447
Location:5 → 57

LIM_LASP; The LIM domain of LIM and SH3 Protein (LASP)

cd11934
Location:200 → 258

SH3_Lasp1_C; C-terminal Src Homology 3 domain of LIM and SH3 domain protein 1

pfam00880
Location:67 → 94

Nebulin; Nebulin repeat

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052558.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

4037109..4057077

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046904350.1 → XP_046760306.1 LIM and SH3 domain protein 1 isoform X1
XM_025143974.2 → XP_024999742.1 LIM and SH3 domain protein 1 isoform X3

Conserved Domains (2) summary

smart00227
Location:42 → 72

NEBU; The Nebulin repeat is present also in Las1

cd11934
Location:144 → 202

SH3_Lasp1_C; C-terminal Src Homology 3 domain of LIM and SH3 domain protein 1
XM_046904351.1 → XP_046760307.1 LIM and SH3 domain protein 1 isoform X2