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CSN5 COP9 signalosome subunit 5 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42000, updated on 26-Aug-2021

Summary

Official Symbol
CSN5provided by FlyBase
Official Full Name
COP9 signalosome subunit 5provided by FlyBase
Primary source
FLYBASE:FBgn0027053
Locus tag
Dmel_CG14884
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA.LD14392; BcDNA:LD14392; CG14884; CH5; CSN-5; csn5; Csn5; dch5; Dch5; DCH5; Dmel\CG14884; Jab1; JAB1; jab1/csn5; JAB1/CSN5; JadBp; l(3)89Cf; l(3)L4032; l(3)M203; Q9XZ58; quo
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Genomic context

See CSN5 in Genome Data Viewer
Location:
89B17-89B17; 3-58 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (16470099..16471406)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (12295821..12297128)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR46029 Neighboring gene Guanylyl cyclase at 89Da Neighboring gene Guanylyl cyclase at 89Db

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the CSN5 gene: The CSN5 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables NEDD8-specific protease activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables NEDD8-specific protease activity IDA
Inferred from Direct Assay
more info
PubMed 
enables isopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables metallopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in axonogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in compound eye photoreceptor cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in female germ-line stem cell population maintenance IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in germ cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in germarium-derived cystoblast division IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in glial cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in male germ-line cyst encapsulation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in multicellular organism development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of hemocyte proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of lamellocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of proteasomal ubiquitin-dependent protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in oocyte anterior/posterior axis specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in oocyte dorsal/ventral axis specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cell cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cellular protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein deneddylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein deneddylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein stabilization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of COP9 signalosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of COP9 signalosome IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in nuclear periphery IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
COP9 signalosome subunit 5
Names
CG14884-PA
CG14884-PB
COP9 complex homolog subunit 5
COP9 complex subunit 5
CSN5-PA
CSN5-PB
JUN activation domain-binding protein-1
Jun activation domain binding protein
drosophila COP9 signalosome homolog 5
NP_001262639.1
NP_477442.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    16470099..16471406
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058094.5NP_477442.1  COP9 signalosome subunit 5, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_477442.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9XZ58
    Related
    FBpp0082743, FBtr0083292
    Conserved Domains (1) summary
    cd08069
    Location:41305
    MPN_RPN11_CSN5; Mov34/MPN/PAD-1 family: proteasomal regulatory protein Rpn11 and signalosome complex subunit CSN5
  2. NM_001275710.1NP_001262639.1  COP9 signalosome subunit 5, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262639.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KHM2
    Related
    FBpp0306602, FBtr0334535
    Conserved Domains (1) summary
    cd08069
    Location:41303
    MPN_RPN11_CSN5; Mov34/MPN/PAD-1 family: proteasomal regulatory protein Rpn11 and signalosome complex subunit CSN5
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