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ACE angiotensin I converting enzyme [ Gallus gallus (chicken) ]

Gene ID: 419953, updated on 19-May-2023

Summary

Official Symbol
ACEprovided by CGNC
Official Full Name
angiotensin I converting enzymeprovided by CGNC
Primary source
CGNC:306
See related
Ensembl:ENSGALG00010023369
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
DCP1
Orthologs
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Genomic context

See ACE in Genome Data Viewer
Location:
chromosome: 27
Exon count:
25
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 27 NC_052558.1 (2300282..2316555)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 27 NC_052599.1 (3518026..3534200)

Chromosome 27 - NC_052558.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121107655 Neighboring gene tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 Neighboring gene cytochrome b561 Neighboring gene potassium voltage-gated channel subfamily H member 6 Neighboring gene DDB1 and CUL4 associated factor 7

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables carboxypeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables chloride ion binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables metallodipeptidase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables metalloendopeptidase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables metallopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metallopeptidase activity NAS
Non-traceable Author Statement
more info
PubMed 
enables peptidyl-dipeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables peptidyl-dipeptidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables peptidyl-dipeptidase activity NAS
Non-traceable Author Statement
more info
PubMed 
enables zinc ion binding ISA
Inferred from Sequence Alignment
more info
PubMed 
Process Evidence Code Pubs
involved_in angiotensin maturation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in bradykinin catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cell population proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in hormone catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in hormone metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in kidney development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of systemic arterial blood pressure IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in primitive erythrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of blood pressure ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of synaptic plasticity ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of systemic arterial blood pressure by renin-angiotensin IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in substance P catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
angiotensin-converting enzyme
Names
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
dipeptidyl carboxypeptidase I
kininase II
NP_001161204.2
XP_046760299.1
XP_046789288.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001167732.2NP_001161204.2  angiotensin-converting enzyme precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000363
    Related
    ENSGALP00010034640.1, ENSGALT00010056963.1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052558.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    2300282..2316555
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046904343.1XP_046760299.1  angiotensin-converting enzyme isoform X1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052599.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    3518026..3534200
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046933332.1XP_046789288.1  angiotensin-converting enzyme isoform X1