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SPEN spen family transcriptional repressor [ Gallus gallus (chicken) ]

Gene ID: 419460, updated on 3-Dec-2024

Summary

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Symbol
SPENprovided by CGNC
Full Name
spen family transcriptional repressorprovided by CGNC
Primary source
CGNC:2675
See related
Ensembl:ENSGALG00010016564
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See SPEN in Genome Data Viewer
Location:
chromosome: 21
Exon count:
15
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 21 NC_052552.1 (4242015..4298272)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 21 NC_052593.1 (4275143..4331401)

Chromosome 21 - NC_052552.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121107386 Neighboring gene filamin binding LIM protein 1 Neighboring gene uncharacterized LOC121107384 Neighboring gene uncharacterized LOC121107385 Neighboring gene zinc finger and BTB domain containing 17 Neighboring gene chloride voltage-gated channel Kb Neighboring gene heat shock protein family B (small) member 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mRNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
msx2-interacting protein; LOW QUALITY PROTEIN: msx2-interacting protein
Names
SMART/HDAC1 associated repressor protein
spen homolog, transcriptional regulator

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052552.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    4242015..4298272
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046903274.1 → XP_046759230.1  LOW QUALITY PROTEIN: msx2-interacting protein isoform X1

    UniProtKB/TrEMBL
    A0A8V0YYC6
    Related
    ENSGALP00010023097.1, ENSGALT00010039900.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052593.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    4275143..4331401
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040689181.2 → XP_040545115.1  msx2-interacting protein isoform X4

    UniProtKB/TrEMBL
    A0A8V0YYC6
    Conserved Domains (7) summary
    PTZ00121
    Location:2028 → 2440
    PTZ00121; MAEBL; Provisional
    PHA03247
    Location:2784 → 3280
    PHA03247; large tegument protein UL36; Provisional
    pfam07744
    Location:3396 → 3556
    SPOC; SPOC domain
    cd12348
    Location:7 → 81
    RRM1_SHARP; RNA recognition motif 1 (RRM1) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
    cd12349
    Location:336 → 409
    RRM2_SHARP; RNA recognition motif 2 (RRM2) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
    cd12350
    Location:436 → 509
    RRM3_SHARP; RNA recognition motif 3 (RRM3) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
    cd12351
    Location:510 → 586
    RRM4_SHARP; RNA recognition motif 4 (RRM4) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins

  2. XM_040689179.2 → XP_040545113.1  msx2-interacting protein isoform X2

    UniProtKB/TrEMBL
    A0A8V0YYC6
    Conserved Domains (7) summary
    PTZ00121
    Location:2028 → 2440
    PTZ00121; MAEBL; Provisional
    PHA03247
    Location:2784 → 3280
    PHA03247; large tegument protein UL36; Provisional
    pfam07744
    Location:3396 → 3554
    SPOC; SPOC domain
    cd12348
    Location:7 → 81
    RRM1_SHARP; RNA recognition motif 1 (RRM1) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
    cd12349
    Location:336 → 409
    RRM2_SHARP; RNA recognition motif 2 (RRM2) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
    cd12350
    Location:436 → 509
    RRM3_SHARP; RNA recognition motif 3 (RRM3) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
    cd12351
    Location:510 → 586
    RRM4_SHARP; RNA recognition motif 4 (RRM4) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins

  3. XM_040689184.2 → XP_040545118.1  msx2-interacting protein isoform X1

    UniProtKB/TrEMBL
    A0A8V0YYC6
    Conserved Domains (8) summary
    PTZ00121
    Location:2027 → 2439
    PTZ00121; MAEBL; Provisional
    PHA03247
    Location:2783 → 3279
    PHA03247; large tegument protein UL36; Provisional
    COG0724
    Location:512 → 666
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam07744
    Location:3395 → 3555
    SPOC; SPOC domain
    cd12348
    Location:7 → 81
    RRM1_SHARP; RNA recognition motif 1 (RRM1) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
    cd12349
    Location:336 → 409
    RRM2_SHARP; RNA recognition motif 2 (RRM2) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
    cd12350
    Location:436 → 509
    RRM3_SHARP; RNA recognition motif 3 (RRM3) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
    cd12351
    Location:510 → 586
    RRM4_SHARP; RNA recognition motif 4 (RRM4) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins

  4. XM_040689180.2 → XP_040545114.1  msx2-interacting protein isoform X3

    UniProtKB/TrEMBL
    A0A8V0YYC6
    Conserved Domains (8) summary
    PTZ00121
    Location:2027 → 2439
    PTZ00121; MAEBL; Provisional
    PHA03247
    Location:2783 → 3279
    PHA03247; large tegument protein UL36; Provisional
    COG0724
    Location:512 → 666
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam07744
    Location:3395 → 3553
    SPOC; SPOC domain
    cd12348
    Location:7 → 81
    RRM1_SHARP; RNA recognition motif 1 (RRM1) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
    cd12349
    Location:336 → 409
    RRM2_SHARP; RNA recognition motif 2 (RRM2) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
    cd12350
    Location:436 → 509
    RRM3_SHARP; RNA recognition motif 3 (RRM3) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
    cd12351
    Location:510 → 586
    RRM4_SHARP; RNA recognition motif 4 (RRM4) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins

  5. XM_040689182.2 → XP_040545116.1  msx2-interacting protein isoform X5

    UniProtKB/TrEMBL
    A0A8V0YYC6
    Conserved Domains (7) summary
    PTZ00121
    Location:1990 → 2402
    PTZ00121; MAEBL; Provisional
    PHA03247
    Location:2746 → 3242
    PHA03247; large tegument protein UL36; Provisional
    pfam07744
    Location:3358 → 3516
    SPOC; SPOC domain
    cd12348
    Location:7 → 81
    RRM1_SHARP; RNA recognition motif 1 (RRM1) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
    cd12349
    Location:336 → 409
    RRM2_SHARP; RNA recognition motif 2 (RRM2) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
    cd12350
    Location:436 → 509
    RRM3_SHARP; RNA recognition motif 3 (RRM3) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
    cl17169
    Location:510 → 562
    RRM_SF; RNA recognition motif (RRM) superfamily

  6. XM_040689183.2 → XP_040545117.1  msx2-interacting protein isoform X6

    UniProtKB/TrEMBL
    A0A8V0YYC6
    Conserved Domains (7) summary
    PTZ00121
    Location:1989 → 2401
    PTZ00121; MAEBL; Provisional
    PHA03247
    Location:2745 → 3241
    PHA03247; large tegument protein UL36; Provisional
    pfam07744
    Location:3357 → 3515
    SPOC; SPOC domain
    cd12348
    Location:7 → 81
    RRM1_SHARP; RNA recognition motif 1 (RRM1) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
    cd12349
    Location:336 → 409
    RRM2_SHARP; RNA recognition motif 2 (RRM2) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
    cd12350
    Location:436 → 509
    RRM3_SHARP; RNA recognition motif 3 (RRM3) found in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
    cl17169
    Location:510 → 562
    RRM_SF; RNA recognition motif (RRM) superfamily
Nucleotide Protein Strain
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