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ARHGEF16 Rho guanine nucleotide exchange factor 16 [ Gallus gallus (chicken) ]

Gene ID: 419386, updated on 3-Apr-2024

Summary

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Official Symbol
ARHGEF16provided by CGNC
Official Full Name
Rho guanine nucleotide exchange factor 16provided by CGNC
Primary source
CGNC:717
See related
Ensembl:ENSGALG00010021459
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See ARHGEF16 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
19
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 21 NC_052552.1 (1020823..1028735, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 21 NC_052593.1 (1052507..1060419, complement)

Chromosome 21 - NC_052552.1Genomic Context describing neighboring genes Neighboring gene WD repeat containing, antisense to TP73 Neighboring gene tumor protein p63 regulated 1-like Neighboring gene multiple EGF like domains 6 Neighboring gene PR/SET domain 16 Neighboring gene uncharacterized LOC419389 Neighboring gene actin-85C-like Neighboring gene actin related protein T2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho guanine nucleotide exchange factor 16
Names
Rho guanine exchange factor (GEF) 16
Rho guanine nucleotide exchange factor (GEF) 16

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052552.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    1020823..1028735 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_417549.7 → XP_417549.6  rho guanine nucleotide exchange factor 16 isoform X5

    UniProtKB/TrEMBL
    A0A8V0ZJV1
    Related
    ENSGALP00010031062.1, ENSGALT00010052037.1
    Conserved Domains (3) summary
    cd11938
    Location:608 → 661
    SH3_ARHGEF16_26; Src homology 3 domain of the Rho guanine nucleotide exchange factors ARHGEF16 and ARHGEF26
    smart00325
    Location:265 → 444
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01221
    Location:466 → 596
    PH_ephexin; Ephexin Pleckstrin homology (PH) domain

  2. XM_046903220.1 → XP_046759176.1  rho guanine nucleotide exchange factor 16 isoform X3

  3. XM_004947372.5 → XP_004947429.3  rho guanine nucleotide exchange factor 16 isoform X5

    UniProtKB/TrEMBL
    A0A8V0ZJV1
    Related
    ENSGALP00010031053.1, ENSGALT00010052024.1
    Conserved Domains (3) summary
    cd11938
    Location:608 → 661
    SH3_ARHGEF16_26; Src homology 3 domain of the Rho guanine nucleotide exchange factors ARHGEF16 and ARHGEF26
    smart00325
    Location:265 → 444
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01221
    Location:466 → 596
    PH_ephexin; Ephexin Pleckstrin homology (PH) domain

  4. XM_004947371.4 → XP_004947428.2  rho guanine nucleotide exchange factor 16 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZJU6, A0A8V0ZJV1
    Related
    ENSGALP00010031057.1, ENSGALT00010052028.1
    Conserved Domains (3) summary
    cd11938
    Location:635 → 688
    SH3_ARHGEF16_26; Src homology 3 domain of the Rho guanine nucleotide exchange factors ARHGEF16 and ARHGEF26
    smart00325
    Location:292 → 471
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01221
    Location:493 → 623
    PH_ephexin; Ephexin Pleckstrin homology (PH) domain

  5. XM_046903221.1 → XP_046759177.1  rho guanine nucleotide exchange factor 16 isoform X5

  6. XM_025142619.3 → XP_024998387.2  rho guanine nucleotide exchange factor 16 isoform X4

    UniProtKB/TrEMBL
    A0A8V0ZJV1, A0A8V0ZJX0
    Related
    ENSGALP00010031051.1, ENSGALT00010052020.1
    Conserved Domains (3) summary
    cd11938
    Location:622 → 675
    SH3_ARHGEF16_26; Src homology 3 domain of the Rho guanine nucleotide exchange factors ARHGEF16 and ARHGEF26
    smart00325
    Location:279 → 458
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01221
    Location:480 → 610
    PH_ephexin; Ephexin Pleckstrin homology (PH) domain

  7. XM_040651267.2 → XP_040507201.1  rho guanine nucleotide exchange factor 16 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZJV1, A0A8V0ZQP0
    Related
    ENSGALP00010031049.1, ENSGALT00010052015.1
    Conserved Domains (4) summary
    cd11938
    Location:639 → 692
    SH3_ARHGEF16_26; Src homology 3 domain of the Rho guanine nucleotide exchange factors ARHGEF16 and ARHGEF26
    smart00325
    Location:296 → 475
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    PHA03247
    Location:4 → 275
    PHA03247; large tegument protein UL36; Provisional
    cd01221
    Location:497 → 627
    PH_ephexin; Ephexin Pleckstrin homology (PH) domain

RNA

  1. XR_005841396.2 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052593.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    1052507..1060419 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040688967.1 → XP_040544901.1  rho guanine nucleotide exchange factor 16 isoform X5

    UniProtKB/TrEMBL
    A0A8V0ZJV1
    Conserved Domains (3) summary
    cd11938
    Location:608 → 661
    SH3_ARHGEF16_26; Src homology 3 domain of the Rho guanine nucleotide exchange factors ARHGEF16 and ARHGEF26
    smart00325
    Location:265 → 444
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01221
    Location:466 → 596
    PH_ephexin; Ephexin Pleckstrin homology (PH) domain

  2. XM_046931425.1 → XP_046787381.1  rho guanine nucleotide exchange factor 16 isoform X3

  3. XM_040688968.2 → XP_040544902.1  rho guanine nucleotide exchange factor 16 isoform X5

    UniProtKB/TrEMBL
    A0A8V0ZJV1
    Conserved Domains (3) summary
    cd11938
    Location:608 → 661
    SH3_ARHGEF16_26; Src homology 3 domain of the Rho guanine nucleotide exchange factors ARHGEF16 and ARHGEF26
    smart00325
    Location:265 → 444
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01221
    Location:466 → 596
    PH_ephexin; Ephexin Pleckstrin homology (PH) domain

  4. XM_040688965.1 → XP_040544899.1  rho guanine nucleotide exchange factor 16 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZJU6, A0A8V0ZJV1
    Conserved Domains (3) summary
    cd11938
    Location:635 → 688
    SH3_ARHGEF16_26; Src homology 3 domain of the Rho guanine nucleotide exchange factors ARHGEF16 and ARHGEF26
    smart00325
    Location:292 → 471
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01221
    Location:493 → 623
    PH_ephexin; Ephexin Pleckstrin homology (PH) domain

  5. XM_046931426.1 → XP_046787382.1  rho guanine nucleotide exchange factor 16 isoform X5

  6. XM_040688966.2 → XP_040544900.1  rho guanine nucleotide exchange factor 16 isoform X4

    UniProtKB/TrEMBL
    A0A8V0ZJV1, A0A8V0ZJX0
    Conserved Domains (3) summary
    cd11938
    Location:622 → 675
    SH3_ARHGEF16_26; Src homology 3 domain of the Rho guanine nucleotide exchange factors ARHGEF16 and ARHGEF26
    smart00325
    Location:279 → 458
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01221
    Location:480 → 610
    PH_ephexin; Ephexin Pleckstrin homology (PH) domain

  7. XM_040688964.2 → XP_040544898.1  rho guanine nucleotide exchange factor 16 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZJV1, A0A8V0ZQP0
    Conserved Domains (4) summary
    cd11938
    Location:639 → 692
    SH3_ARHGEF16_26; Src homology 3 domain of the Rho guanine nucleotide exchange factors ARHGEF16 and ARHGEF26
    smart00325
    Location:296 → 475
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    PHA03247
    Location:4 → 275
    PHA03247; large tegument protein UL36; Provisional
    cd01221
    Location:497 → 627
    PH_ephexin; Ephexin Pleckstrin homology (PH) domain

RNA

  1. XR_005855574.2 RNA Sequence

Nucleotide Protein Strain
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