Format

Send to:

Choose Destination

PER3 period circadian clock 3 [ Gallus gallus (chicken) ]

Gene ID: 419366, updated on 14-Feb-2019

Summary

Symbol
PER3provided by CGNC
Full Name
period circadian clock 3provided by CGNC
Primary source
CGNC:50977
See related
Ensembl:ENSGALG00000000573
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
gPER3
Summary
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. [provided by RefSeq, Feb 2014]
Orthologs

Genomic context

See PER3 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
25
Annotation release Status Assembly Chr Location
104 current GRCg6a (GCF_000002315.5) 21 NC_006108.5 (291189..310409, complement)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 21 NC_006108.4 (272583..291808, complement)
102 previous assembly Gallus_gallus-4.0 (GCF_000002315.3) 21 NC_006108.3 (289473..308698, complement)

Chromosome 21 - NC_006108.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107054906 Neighboring gene TNF receptor superfamily member 9 Neighboring gene urotensin 2 Neighboring gene vesicle-associated membrane protein 3 Neighboring gene calmodulin binding transcription activator 1 Neighboring gene translation initiation factor IF-2-like

Genomic regions, transcripts, and products

Pathways from BioSystems

  • Herpes simplex infection, organism-specific biosystem (from KEGG)
    Herpes simplex infection, organism-specific biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
  • Herpes simplex infection, conserved biosystem (from KEGG)
    Herpes simplex infection, conserved biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...

General gene information

Homology

General protein information

Preferred Names
period circadian protein homolog 3
Names
circadian clock protein
period homolog 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001289779.2NP_001276708.1  period circadian protein homolog 3

    Status: PROVISIONAL

    Source sequence(s)
    AADN05000197
    UniProtKB/TrEMBL
    E1C8E2
    Related
    ENSGALP00000000796.5, ENSGALT00000000797.6
    Conserved Domains (4) summary
    cd00130
    Location:269361
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam08447
    Location:269357
    PAS_3; PAS fold
    pfam12114
    Location:9921155
    Period_C; Period protein 2/3C-terminal region
    cl24006
    Location:116189
    YidC_periplas; YidC periplasmic domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCg6a Primary Assembly

Genomic

  1. NC_006108.5 Reference GRCg6a Primary Assembly

    Range
    291189..310409 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004947317.3XP_004947374.1  period circadian protein homolog 3 isoform X3

    Conserved Domains (4) summary
    cd00130
    Location:269361
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam08447
    Location:269357
    PAS_3; PAS fold
    pfam12114
    Location:9911154
    Period_C; Period protein 2/3C-terminal region
    cl24006
    Location:116189
    YidC_periplas; YidC periplasmic domain
  2. XM_004947316.3XP_004947373.1  period circadian protein homolog 3 isoform X2

    Conserved Domains (4) summary
    cd00130
    Location:269361
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam08447
    Location:269357
    PAS_3; PAS fold
    pfam12114
    Location:9911154
    Period_C; Period protein 2/3C-terminal region
    cl24006
    Location:116189
    YidC_periplas; YidC periplasmic domain
  3. XM_025142495.1XP_024998263.1  period circadian protein homolog 3 isoform X4

    Conserved Domains (2) summary
    cd00130
    Location:269361
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam12114
    Location:9881158
    Period_C; Period protein 2/3C-terminal region
  4. XM_015296850.2XP_015152336.1  period circadian protein homolog 3 isoform X7

    Conserved Domains (4) summary
    cd00130
    Location:229321
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam08447
    Location:229317
    PAS_3; PAS fold
    pfam12114
    Location:9521115
    Period_C; Period protein 2/3C-terminal region
    cl24006
    Location:76149
    YidC_periplas; YidC periplasmic domain
  5. XM_015296851.2XP_015152337.1  period circadian protein homolog 3 isoform X8

    Conserved Domains (4) summary
    cd00130
    Location:178270
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam08447
    Location:178266
    PAS_3; PAS fold
    pfam12114
    Location:9011064
    Period_C; Period protein 2/3C-terminal region
    cl24006
    Location:2598
    YidC_periplas; YidC periplasmic domain
  6. XM_004947319.3XP_004947376.1  period circadian protein homolog 3 isoform X6

    Conserved Domains (4) summary
    cd00130
    Location:269361
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam08447
    Location:269357
    PAS_3; PAS fold
    pfam12114
    Location:9921134
    Period_C; Period protein 2/3C-terminal region
    cl24006
    Location:116189
    YidC_periplas; YidC periplasmic domain
  7. XM_417528.6XP_417528.4  period circadian protein homolog 3 isoform X5

    Conserved Domains (4) summary
    cd00130
    Location:269361
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam08447
    Location:269357
    PAS_3; PAS fold
    pfam12114
    Location:9921135
    Period_C; Period protein 2/3C-terminal region
    cl24006
    Location:116189
    YidC_periplas; YidC periplasmic domain
  8. XM_004947315.3XP_004947372.1  period circadian protein homolog 3 isoform X1

    Conserved Domains (4) summary
    cd00130
    Location:269361
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam08447
    Location:269357
    PAS_3; PAS fold
    pfam12114
    Location:9921154
    Period_C; Period protein 2/3C-terminal region
    cl24006
    Location:116189
    YidC_periplas; YidC periplasmic domain
  9. XM_025142496.1XP_024998264.1  period circadian protein homolog 3 isoform X9

    Conserved Domains (1) summary
    cd00130
    Location:269361
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

RNA

  1. XR_001469724.2 RNA Sequence

  2. XR_001469723.2 RNA Sequence

  3. XR_003071520.1 RNA Sequence

  4. XR_003071519.1 RNA Sequence

  5. XR_003071517.1 RNA Sequence

  6. XR_003071518.1 RNA Sequence

  7. XR_003071516.1 RNA Sequence

  8. XR_213511.3 RNA Sequence

  9. XR_001469725.2 RNA Sequence

  10. XR_213513.3 RNA Sequence

Support Center